Heart Disease Archive

Research we're watching

A unique diabetes drug shows heart-related benefits in people with diabetes who also have recently worsening heart failure or kidney disease, according to two new studies.

The drug, sotagliflozin (Zynquista), belongs to a class of drugs called SGLT2 inhibitors, which cause the kidneys to release more sugar into the urine. The drug is also an SGLT1 inhibitor, meaning it decreases sugar absorption in the intestines. This dual action lowers high blood sugar, the hallmark of diabetes. In people with kidney disease, sotagliflozin lowered the total number of deaths from cardiovascular disease and hospitalizations and urgent visits for heart failure by about 26% compared with a placebo. In a second study, which included people with recently worsening heart failure, those taking the drug had a 33% decrease in those same heart-related measures compared with a placebo.

Research we're watching

Doing vigorous exercise for just 12 minutes triggers changes in blood levels of substances linked to cardiovascular health, new research finds.

The study used data from 411 middle-aged adults from the Framingham Heart Study. Researchers measured levels of 588 substances involved in metabolism (metabolites) in the volunteers' blood before and immediately after 12 minutes of vigorous exercise on an exercise bike.

Your partner's flawed health behaviors may be harming your heart.

It's been said that the longer couples stay together the more they look alike. As it turns out, the resemblance may be more than skin-deep. A study published online Oct. 26, 2020, by JAMA Network Open found that couples' health behavior and heart disease risk factors also look alike — for better or worse.

"We know, even from personal experience, that couples share similar behaviors that can affect health, but it was surprising to find the high levels of shared unhealthy behaviors within couples," says the study's lead author, Dov Shiffman, a senior scientific fellow at the medical testing company Quest Diagnostics.

During waking hours you may feel your heart rate fluctuating, and activity or intense emotions can cause it to spike. But what happens to your heart rate when you sleep? It varies then too, depending on the phase of sleep you are in.

The culture of American medicine has long believed and supported the idea that more early detection and treatment is best. But some testing is costly, invasive and carries needless risks, and some conditions go away on their own. Early detection and treatment can be lifesaving — just not for every health issue.

Regardless of your size or fitness level, exercise has multiple benefits. Almost anything that gets you moving counts, and some activity is always better than none. These suggestions can help you make exercise work for you.

For people recently diagnosed, taming the heart's rhythm rather than slowing it down may be a better approach.

The heart rhythm disorder known as atrial fibrillation (afib) occurs when the heart's electrical system goes awry. Instead of the heart's natural pacemaker creating a steady beat, the heart's upper chambers (atria) pulsate rapidly — up to hundreds of times per minute. Most of the electrical impulses telling the lower chambers (ventricles) to contract don't get through but many do, triggering a racing, irregular heartbeat that can leave people dizzy, breathless, or fatigued.

Therapies to tackle this common arrhythmia have improved over the years. Now, new findings suggest it may be time to rethink the treatment for people newly diagnosed with afib (see "Afib: Rhythm vs. rate control").

Spontaneous coronary artery dissection is an underrecognized but important cause of heart attack, especially in younger women.

Most heart attacks happen when a blood clot blocks an artery feeding the heart. But a small percentage result from a tear in the inner wall of one of the heart's arteries. The resulting flap or swelling inside the artery wall obstructs normal blood flow. Known as a spontaneous coronary artery dissection, or SCAD, the condition strikes both sexes but is more common in women.

In women who are under 50, SCAD is the most common reason for acute coronary syndrome. This medical emergency refers to inadequate blood flow to the heart; it includes both heart attacks and unstable angina (sudden chest pain that occurs at rest).

Editor's note: This year, we're highlighting fruits on this page. Starting in February, we'll showcase a different type of fruit or group of related fruits, such as citrus fruits or melons. We'll include ideas about the best ways to add more of these heart-healthy foods into your diet.

If you eat berries with breakfast, snack on a banana, and toss some cubed apple or pear in your dinner salad, you can easily meet the recommended amount of fruit for adults, which is 1.5 to 2 cups per day. But such habits are unusual: Fewer than one in 10 Americans consumes even the minimum recommended amount of fruit, according to a national federal survey.

Research we're watching

Walking even at a "casual" pace — covering a mile in 30 minutes — five days a week may lower the odds of high blood pressure in postmenopausal women, a new study finds.

Researchers relied on data from more than 83,000 women ages 50 to 79 who did not have high blood pressure. When they joined the study, they filled out questionnaires about their walking speed and duration. This was followed by yearly questionnaires that included checking for a diagnosis of high blood pressure.