Heart Disease Archive

For people with a family history of early heart disease, getting a coronary artery calcium (CAC) scan plus intensive coaching and a statin may help limit the progression of the plaque in their arteries, according to a 2025 study.

A 2025 study found that a new type of medication may safely slow the progression of aortic stenosis (narrowing of the aortic valve) and delay the need for valve replacement.

About one in every 20 people over age 65 has a stiff, narrowed aortic valve. A Harvard physician describes his experience with this condition, called aortic stenosis, from the heart murmur detected at age 66 to his open-heart surgery a decade later. After his diagnosis, he received echocardiograms every one to two years to check the valve, and later a stress echocardiogram. Because the echocardiogram revealed an aortic aneurysm, he had open-heart surgery so the surgeon could repair the valve and the aneurysm during the same operation.

A 2025 research review suggested that women with certain gynecological disorders, such as polycystic ovary syndrome, endometriosis, heavy periods, and irregular menstrual cycles, have higher risks of cardiovascular and cerebrovascular disease.

Since its introduction in 1998, catheter ablation for atrial fibrillation has greatly improved, thanks to advances in the instruments, imaging techniques, and energy sources used during the procedure. The resulting increases in safety and effectiveness have transformed ablation into a routine procedure. For many people newly diagnosed with this heart rhythm disorder, ablation is now the first treatment offered.

People with a family history of heart disease and high LDL cholesterol should consult their doctor about lowering their LDL levels to less than 70 milligrams per deciliter, which often means taking a statin, eating a healthier diet and exercising regularly.

Older people with atrial fibrillation are sometimes advised to stop taking clot-prevention drugs due to fears about bleeding. But a 2025 study suggests that the risk of stroke and heart attack from stopping the drugs outweighs the risk of bleeding.

To optimize cardiovascular health, the best strategy may be a workout that combines three types of exercise: moderate-intensity aerobic exercise, vigorous-intensity aerobic exercise, and strength training. Moderate activity burns calories and boosts metabolism, which helps control weight. Moderate-to-vigorous exercise also helps dampen the body's "fight or flight" response, which plays a role in chronic stress and anxiety. Aerobic exercise in general also helps the heart to become more efficient and blood vessels to become more flexible. Strength training makes the body more efficient at burning fat for energy and helps improve insulin sensitivity.

Coronary computed tomography angiography (CCTA) creates a 3D image of the heart and its blood vessels, revealing both obstructive and nonobstructive plaque. Most heart attacks occur when smaller, nonobstructive plaques rupture and form a clot that triggers a heart attack. Used to assess people with stable angina, CCTA may prevent heart attacks by improving how cardiologists find and treat heart disease.

A 2025 studyfound that intermuscular fat—fat stored within muscle tissue—may increase a person's risk of heart disease.