Diseases & Conditions Archive

PrEP (pre-exposure prophylaxis) is a daily medication taken to prevent HIV infection. While multiple studies show PrEP is effective, relatively few of those who might benefit are taking it. Will a 10-year initiative to reduce rates of HIV and a new formulation of PrEP help?

Ask the doctors

Q. I've had endometriosis since I was in my 30s. I'm now approaching menopause. Will my symptoms get better or even go away after menopause?

A. Possibly, but not always. Endometriosis is a condition in which tissue that resembles the tissue that lines the uterus, called endometrial tissue, grows in other locations inside the body. Typically, it grows on structures and organs in the pelvis, such as the ovaries, fallopian tubes, bladder, or bowels. When a woman menstruates, this tissue behaves like the lining of the uterus and bleeds. But because this blood has no way to exit the body, it pools inside. This leads to pain, inflammation, and scarring.

Bacteria and mold can accumulate in various parts of the device. But regular equipment cleaning reduces risks.

Continuous positive airway pressure (CPAP) can be hard to get used to. The mask may feel bulky, or it may feel strange to have air blowing in as you try to breathe. That keeps many people from using a treatment that may, in fact, be a lifesaver (see "What is CPAP?").

People also can be put off because they've heard that a dirty CPAP machine can make you sick. Is that true? "Yes, if you don't clean the machine regularly," says Dr. Lawrence Epstein, a sleep expert at Harvard-affiliated Brigham and Women's Hospital.

Doctors say three recently approved migraine prevention drugs are helping people have fewer headaches.

For people with frequent, debilitating migraine headaches, 2018 brought encouraging news. The FDA approved three new medications — erenumab (Aimovig), fremanezumab (Ajovy), and galcanezumab (Emgality) — the first drugs designed specifically to prevent migraines and reduce their frequency, intensity, and duration.

It was a big development, since other medications used to stop migraines were created to control other conditions, such as seizures, depression, high blood pressure, or an irregular heartbeat. But their side effects (such as weight gain, dizziness, or fuzzy thinking) often cause people to skip treatment.

Research we're watching

Can emotional stress harm your bones? A new study found an association between stressful social relationships and bone problems in women. The study, which was published online July 9 by the Journal of Epidemiology & Community Health, found that women who reported high levels of social stress had lower bone density six years later. The study looked at more than 11,000 postmenopausal women. At the time of enrollment, the women filled out a questionnaire that asked them to rate their social stress levels and had their bone density measured both at enrollment and six years later at a follow-up appointment. Women who had reported high levels of stress at the initial interview showed a bigger decline in bone density at the follow-up compared with women who'd initially reported lower stress levels. This was true even after the researchers adjusted for other factors that may affect bone health, such as age, weight, smoking, alcohol use, and education, among others. The authors speculated that stress may harm bone health because stress leads to higher blood cortisol levels, a well-established reason for lower bone density. Further study is needed to understand and confirm the results.

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Some men with an enlarged prostate gland (benign prostatic hyperplasia, or BPH for short) eventually start to experience urinary incontinence, the involuntary discharge of urine. The incontinence can be related to overactive bladder, one of the changes in bladder function caused by BPH.

Normally, the brain says "time to go" when your bladder is only partially full. That gives you a fair warning to find a place to relieve yourself. When you decide to let go, a valve called the urinary sphincter opens to allow the bladder to drain. Muscles in the bladder wall squeeze inward to empty the storage tank.

Nerve damage might be causing everything from low blood pressure to gastrointestinal distress without your knowing it.

Doctors have long known peripheral neuropathy as a nerve condition that causes reduced sensation, tingling, weakness, or pain in the feet and hands. But those symptoms may be just the tip of the iceberg. Doctors are now learning that neuropathy can cause many more problems.

What is peripheral neuropathy?

Peripheral neuropathy refers to damage to the peripheral nerves throughout the body. These nerves carry messages to and from the brain.