Diseases & Conditions Archive

Burning mouth syndrome affects about 2% of people, with women up to seven times more likely than men to be diagnosed. Symptoms include burning sensations in the lips, mouth, or throat as well as stabbing pain, tingling, a sour or metallic taste, or the sense that something is crawling inside the mouth. Women’s hormone dips during perimenopause and beyond may play a role in the condition, and stress and anxiety are also considered risk factors. To confirm the diagnosis, doctors must first rule out other potential causes of symptoms.

In gastroesophageal reflux disease (GERD), stomach acid washes backward into the esophagus. This can cause symptoms such as heartburn, an acidic or metallic taste in the mouth, hoarse voice, chest pain, dry cough, post-nasal drip, or trouble swallowing. Symptoms can overlap with those of several other conditions. These include hiatal hernia, functional dyspepsia, eosinophilic esophagitis, esophageal spasms, or heart attack. Distinguishing GERD from other conditions may involve various tests, including an endoscopy to view the esophagus lining.

A 2025 randomized controlled trial found that GLP-1 receptor agonists, the blockbuster drugs approved to treat diabetes and obesity, boosted the walking ability of people with diabetes and peripheral artery disease (PAD) in the legs. The news is encouraging, since there are few effective treatments for PAD—reduced blood flow in the limbs that leads to pain with activity. However, it will take more evidence before doctors feel comfortable prescribing GLP-1s if a person only has PAD.

The digestion process slows as one ages, causing digested food to take its time moving along the gastrointestinal tract from the stomach through the intestines. The longer food stays in the digestive tract, the more opportunity there is for gas to be produced and build up, resulting in bloating. Recurrent bloating also can be caused by people’s reactions to certain foods, especially those that contain sugars called FODMAPs. Adjusting one’s diet to avoid trigger foods and taking over-the-counter remedies can help prevent and manage problem bloating.

Havard researchers have identified biomarkers that appear to capture tinnitus severity for the first time. Scientists made the connection after analyzing the facial responses and pupil dilation of study participants as they listened to pleasant, neutral, or unpleasant sounds. The findings, when fed to a computer model, accurately predicted the severity of symptoms participants had reported on questionnaires. Scientists hope the biomarkers will lead to tools that gauge tinnitus severity and treatment effectiveness.