Diseases & Conditions Archive

Q. My platelet count has always been on the low side — 110,000. I don't have any symptoms. But a recent lab report mentioned "giant platelets." Is this something to worry about?

A. Platelets are tiny cell fragments that circulate in the blood and help it clot. They form clots by sticking to one another and by releasing chemicals that promote other aspects of clotting, which is an elaborate, multistep process.

Poor night vision is the result of changes in the pupil, lens, and retina. Does eating carrots help? Probably not for well-nourished Americans.

It's been said that the eyes are the windows to the soul. At a more mundane level, they also say a lot about how old we are. With advancing years, we're prone to a number of serious — and less-serious (but bothersome) — conditions of the eye.

Tennis elbow is the common term for lateral epicondylitis, an inflammatory condition of the tendon that connects the extensor muscles of the lower arm to a bony prominence on the outside of the elbow called the lateral epicondyle. The condition causes pain at the point where the tendon attaches to the epicondyle. The pain may radiate to the forearm and wrist, and in severe cases, grip strength may lessen. It can become difficult to perform simple actions like lifting a cup, turning a key, or shaking hands.

As many as half of all people who play racket sports have the condition, but most people who have tennis elbow didn't acquire it by playing tennis, squash, or racquetball. It can result from any activity that involves twisting or gripping motions in which the forearm muscles are repeatedly contracted against resistance, such as pruning bushes or pulling weeds, using a screwdriver, or playing a violin. Tennis elbow is an occupational hazard for professional gardeners, dentists, and carpenters.

After treatment, you may see better than you have in decades.

Have you noticed that colors aren't as bright as they used to be? That there is more glare at night? That your distance vision is hazy, even with new glasses?

Q. For years, I have had recurrent cold sores and took antiviral drugs to treat the outbreaks. A friend suggested that I take daily lysine.  What's the evidence that it works?

A. Cold sores (sometimes called fever blisters) are painful fluid-filled lesions on or near the lips that are caused by the herpes simplex virus (HSV). There are two kinds of HSV: HSV-1, which causes most cold sores, and HSV-2, which is mostly responsible for genital herpes. HSV-1 infection is very common and easily transmitted by kissing or other contact with saliva. Once you're infected, the virus lays dormant in the nerve cells that supply sensation to the skin. When the virus becomes active, it travels to the skin surface and multiplies, causing an outbreak.

What you eat can fuel or cool inflammation, a key driver of heart disease, diabetes, and other chronic conditions.

Inflammation is an essential part of the body's healing system. Without it, injuries would fester and simple infections could be deadly. Too much of a good thing, though, is downright dangerous. Chronic low-grade inflammation is intimately involved in all stages of atherosclerosis, the process that leads to cholesterol-clogged arteries. This means that inflammation sets the stage for heart attacks, most strokes, peripheral artery disease, and even vascular dementia, a common cause of memory loss. Think of it as friendly fire "" yourself attacking yourself.

Inflammation doesn't happen on its own. It is the body's response to a host of modern irritations that our Stone Age genes haven't quite caught up to. The main ones are smoking, lack of exercise, high-fat and high-calorie meals, and highly processed foods.

Q. I've been taking Prilosec for many years for GERD. Recently, I once read that long-term use of proton pump inhibitors could increase the risk of stomach cancer. Your opinion?

A. Prilosec is a pump inhibitor (PPI). These drugs have revolutionized the treatment of gastroesophageal reflux disease (GERD), in which stomach acid flows back into the esophagus and causes heartburn.

Proper eye care can limit vision loss from most glaucoma — and prevent one of its most serious forms.

Glaucoma is a group of eye diseases that cause vision loss and blindness through damage to the optic nerve. Several factors contribute to its development, but the main culprit is elevated intraocular pressure, that is, pressure within the eye.

Theoretically, glaucoma can be managed and vision loss prevented or minimized with early detection and medical treatment to control intraocular pressure. But the most common form, called open-angle glaucoma, progresses so slowly and subtly that symptoms, such as blind spots and reduced peripheral vision, may go unnoticed until the disease has advanced and vision loss is inevitable.

Removing a Speck From the Eye

Occasionally, an eyelash or speck of dirt gets into the eye and causes irritation. If tears that form do not wash out the object, it can sometimes be removed by pulling the upper eyelid down over the lower eyelid. The lashes of the lower eyelid may brush out any foreign object that is caught under the upper lid.

If this does not work, try either of the procedures described below.

Hard to detect and quick to spread, pancreatic cancer is among the deadliest of cancers. Scientists hope that genetic research will make it more like other cancers-a treatable disease. But even if it's caught while confined to the pancreas-and it rarely is-just 16% of patients are alive five years after the initial diagnosis. By comparison, the five-year survival rate for localized breast cancer is 86%. If the cancer has spread beyond the pancreas, the likelihood of living another five years is just 2%. Only the statistics for liver cancer are as grim.

Fortunately, pancreatic cancer is uncommon compared with other major cancers. About 50,000 new cases are diagnosed every year in the United States, in contrast to about 250,000 new cases of breast cancer, and 225,000 new cases of lung cancer. But because it's so untreatable, pancreatic cancer causes about 40,000 deaths each year. It is the 4^th leading cause of cancer death.