Colorectal Cancer Archive

Metformin, a medicine prescribed to treat type 2 diabetes, also has cardiovascular benefits and is used off-label to treat other conditions. Interest is growing in its potential to help lower risks for other serious health problems and even slow aspects of aging, but which of these benefits, if any, apply to people who do not have diabetes?

A 2023 study suggests that having diabetes may be tied to a higher risk of developing colorectal cancer than not having diabetes.

Some products people use daily have been associated with increased cancer risks. Examples are aspartame, nonstick cookware, mattresses, cleaning products, and personal care products. While evidence is mixed, most consumer products confer low cancer risks, if any. People who are concerned about exposure to these common products should find alternatives. People can also reduce their overall cancer risks by stopping smoking, avoiding alcohol, exercising, and maintaining a healthy weight.

Lung cancer kills more Americans than any other cancer. The latest guidelines from the American Cancer Society aim to reduce deaths by considerably expanding the pool of people who seek annual, low-dose CT lung screening scans.

Lynch syndrome is an inherited condition that predisposes people to colorectal, uterine, ovarian, and other forms of cancer. Genetic testing can pinpoint Lynch syndrome, and genetic counseling is also recommended. People with Lynch syndrome need frequent cancer screenings and should watch for symptoms. Women with Lynch syndrome are also advised to undergo risk-reducing surgery that removes the ovaries, fallopian tubes, and uterus between ages 35 and 40, unless a woman is planning another pregnancy.

In a 2023 study, people who didn't exercise regularly but accumulated three and a half minutes of vigorous daily activity (such as stair climbing) had a 32% lower risk for developing cancer, compared with non-exercisers who didn't do any vigorous activity.

According to a 2023 observational study, greater cardiorespiratory fitness in men was linked to a lower risk of death from colon, lung, or prostate cancer.

In the US population as a whole, deaths from colon cancer have been declining, but in people under 50 that rate has increased. Most major medical organizations recommend screening beginning at age 45 for people at average risk.

Death risk from breast cancer that's treated early appears to be falling, according to a large 2023 study. The risk of dying from the cancer within five years dropped from about 14% for women diagnosed in the 1990s to about 5% for women diagnosed between 2010 and 2015.

Melanoma kills about 8,000 Americans each year. Most people are at low risk of melanoma and don't need annual skin cancer screenings. People should be screened each year if they have risk factors such as dozens of atypical moles, a family history of melanoma or atypical moles, an earlier skin cancer, certain genetic mutations or predisposition, immune-suppressing therapy after organ transplantation or for inflammatory bowel disease, a history of blistering sunburns, or substantial tanning bed use.