Cholesterol Archive

For most people, statins are still the best way to lower harmful LDL cholesterol. But two newer drugs may be promising additions or alternatives for those with stubbornly high LDL levels. Bempedoic acid, which lowers LDL by about 25%, works in a manner similar to statins but may help reduce muscle-related side effects seen with statins. Inclisiran interferes with a protein that’s involved with regulating LDL production in the liver; it lowers LDL by about 50%.

For people in their 80s and beyond, the advice for preventing and treating heart disease is similar to that for young people, especially with respect to staying physically active. But octogenarians may need to adjust their medication regimens. Low-dose aspirin is not recommended after age 70, and doses of anti-clotting medications may need to be reduced. Some people may also need to dial back their blood pressure medications if they experience side effects such as dizziness.

People who follow a low-carbohydrate/high-fat diet for weight loss often eat high amounts of saturated fat. Even though saturated fat can contribute to cardiovascular disease, a 2021 study suggests that eating higher amounts might not be bad for heart health in the short term.

It is possible to experience a stroke without symptoms. Addressing cardiovascular risk factors can help lower the risk.

Statin therapy can help lower the risk of developing new plaques in the arteries and having a heart attack, although the effect may not show up on coronary artery calcium scans that measure the amount of calcium in the walls of the heart's arteries.