Addiction Archive

The trials and challenges of this year are weighing heavily on many people, but attempting to employ positive psychology to put personal struggles in context, and accepting the ups and downs life brings, can ultimately increase positive feelings and provide perspective.

Research we're watching

A recent study found that nearly one in 10 people who received opioid pain relievers following heart surgery continued to take them for three to six months — a time point when no one should still be experiencing pain from the operation.

The study included nearly 36,000 people with private health insurance who had a coronary artery bypass graft (known as CABG or bypass surgery) or a heart valve replacement between 2003 and 2016. People who were prescribed more than 40 5-mg tablets of oxycodone (Oxycontin, Roxicodone, others) or an equivalent amount of a similar drug were at a much higher risk of prolonged opioid use than people who were prescribed lower doses. Other factors that increased a person's odds of taking opioids long-term included having CABG, being female, or having a history of chronic pain or alcoholism.

News briefs

Probiotic supplements containing helpful bacteria and yeast are marketed as a way to maintain a diverse mix of healthy gut microbes. Now, a review published online July 6, 2020, by BMJ Nutrition, Prevention & Health suggests that probiotic supplements may help relieve depression symptoms. Scientists evaluated seven clinical trials from the past 15 years, which tested a total of 12 different strains of helpful bacteria. One trial in the review tested a "prebiotic," a type of plant fiber that provides food for gut bacteria. Scientists concluded that 11 of these probiotics, either alone or combined with prebiotics, were potentially useful for relieving symptoms of depression, perhaps by reducing inflammation that could affect brain function. The studies were small and short-term, but taken together, they suggest a gut-based approach to maintaining emotional well-being is worth pursuing. In the meantime, talk therapy, exercise, and medications remain the most effective approaches to treat depression. To support your gut health without expensive probiotic supplements, enjoy foods that naturally contain probiotics, such as yogurt, kefir, and sauerkraut. The prebiotic powers of whole grains also may support a healthy gut.

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People who regularly worried about the future and dwelled on the past saw larger drops in cognition and had more harmful brain proteins than those who didn't.

Chronic worrying or ruminating could be bad for your brain. A study published online June 7, 2020, by Alzheimer's & Dementia linked these negative thinking patterns to brain changes that could be associated with Alzheimer's disease.

Study authors found that older adults who regularly engaged in what the authors called repetitive negative thinking were more likely to experience cognitive decline, including memory problems, than those who didn't. They also had higher levels of the proteins beta-amyloid and tau in their brains. The accumulation of these proteins, which create damaging clumps known as plaques and tangles in the brain, is a hallmark of Alzheimer's that begins in the earliest stages of the disease — even before an individual experiences visible symptoms of dementia.

With the introduction of benzodiazepines such as chlordiazepoxide (Librium) and diazepam (Valium) in the early 1960s, a new era in the treatment of insomnia and anxiety began. The benzodiazepines were more effective and far safer than the older drugs — barbiturates, meprobamate, and glutethimide — that had been prescribed for these purposes. For many years, benzodiazepines continued to be the most popular prescription tranquilizers and sedatives. Since the mid-1980s, new alternatives have been assuming some of these roles, but benzodiazepines are not about to leave the stage.

More than a dozen benzodiazepines are available by prescription. Benzodiazepines have a common basic chemical structure, and they all increase activity at receptors for the neurotransmitter gamma-aminobutyric acid (GABA). This transmitter inhibits the activity of neurons, slowing down the brain and nervous system. Benzodiazepines differ mainly in how quickly they are absorbed, how long their effects last, and how long they take to leave the body.

More than six months into the pandemic, it’s clear that we are going to be living with it for some time, and that expectations of life soon returning to normal are not realistic. This is a good time to assess the adjustments we’ve made and see how we can make different choices to get ourselves and our families through the challenge.

As the school year begins, plans for how learning will happen are in flux, and may change rapidly. With so much uncertainty, parents will want to limit confusion and create as much structure as they can for their children in this difficult situation.

Shifting your thinking and practicing deep breathing can help when you're stuck in an intense emotional moment.

At some point, we've all gotten stuck in a "meltdown" moment — an overwhelming feeling of anger or stress that was difficult to shake off. "Feeling overwhelmed makes it harder to identify ways to get unstuck; the options seem limited, which can create a sense of hopelessness or despair. Additionally, negative memories may come to mind more readily, and we may filter out useful ways of viewing the situation at hand," says Abby Altman, an associate psychologist at Harvard-affiliated Brigham and Women's Hospital.

But there are ways to shift your focus and break out of extremely emotional moments. Take note of the following tips so you can put them to work if a meltdown strikes.

Not all memory issues are cause for concern. Here is how to manage those annoying everyday lapses.

Everyone experiences the occasional "senior moment" as they age. You may misplace everyday items, fail to recall the name of someone you just met, or forget to do something. While these memory slips can be embarrassing and stressful, they usually don't mean that you are on a path to dementia.

"Some degree of memory lapses is a normal part of aging," says Lydia Cho, a neuropsychologist with Harvard-affiliated McLean Hospital. "You can't expect to hold on to all information you've gathered throughout your life, whether it was long ago or recent. It's not realistic or adaptive."