Worries on your mind
Study authors found that older adults who regularly engaged in what the authors called repetitive negative thinking were more likely to experience cognitive decline, including memory problems, than those who didn't. They also had higher levels of the proteins beta-amyloid and tau in their brains. The accumulation of these proteins, which create damaging clumps known as plaques and tangles in the brain, is a hallmark of Alzheimer's that begins in the earliest stages of the disease — even before an individual experiences visible symptoms of dementia.
To continue reading this article, you must log in.
Subscribe to Harvard Health Online Plus (HHO+) to unlock expert-backed health insights, personalized tools, and exclusive resources to feel your best every day.
Here’s what you get with your HHO+ membership:
- Unlimited access to all Harvard Health Online content
- 4 expertly curated newsletters delivered monthly
- Customized website experience aligned to your health goals
- In-depth health guides on topics like sleep, exercise, and more
- Interactive features like videos and quizzes
- Members-only access to exclusive articles and resources
I’d like to subscribe to HHO+ for $4.99/month to access expert-backed content to help make smart, informed decisions about my well-being.
Sign Me UpAlready a member? Login ».
Disclaimer:
As a service to our readers, Harvard Health Publishing provides access to our library of archived content. Please note the date of last review or update on all articles.
No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician.