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Heart Health

New cholesterol guidelines recommend Lp(a) blood test

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By , Executive Editor, Harvard Heart Letter
  • Reviewed by Robert H. Shmerling, MD, Senior Faculty Editor, Harvard Health Publishing; Editorial Advisory Board Member, Harvard Health Publishing
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A gloved hand holds a tube containing a blood sample; the tube is labeled lipoprotein (a) test.Circulation

About one in five people has high blood levels of Lp(a), which increases the odds of a heart attack even in people with no other risk factors for heart disease. High Lp(a) - defined as 125 nanomoles per liter (nmol/L) or greater - is linked to a 40% increase in long-term risk of heart attack or stroke. Risk rises further with higher values: at 250 nmol/L, risk doubles, and at 350 nmol/L, risk triples. Your genes largely determine your Lp(a) value, which is minimally affected by your eating and exercise habits.

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About the Author

photo of Julie Corliss

Julie Corliss, Executive Editor, Harvard Heart Letter

Julie Corliss has been the executive editor of the Harvard Heart Letter since 2013. She also writes for the Harvard Health Letter, Harvard Women’s Health Watch, and Harvard Men’s Health Watch, as well as for Harvard … See Full Bio
View all posts by Julie Corliss

About the Reviewer

photo of Robert H. Shmerling, MD

Robert H. Shmerling, MD, Senior Faculty Editor, Harvard Health Publishing; Editorial Advisory Board Member, Harvard Health Publishing

Dr. Robert H. Shmerling is the former clinical chief of the division of rheumatology at Beth Israel Deaconess Medical Center (BIDMC), and is a current member of the corresponding faculty in medicine at Harvard Medical School. … See Full Bio
View all posts by Robert H. Shmerling, MD
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