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New concerns about anticholinergic medications

Anticholinergics, a group of medications that includes many over-the-counter and prescription drugs, are well known for causing confusion in older adults. Common medications with anticholinergic properties include medications to treat overactive bladder, such as oxybutynin (Ditropan); medications to treat allergies and sleeping problems, such as diphenhydramine (Benadryl, Sominex, Unisom); and medications used to treat depression, such as amitriptyline (Elavil). It's generally believed that confusion that may develop from anticholinergics clears up when someone stops taking the drugs. But now it appears that the medications are associated with a more permanent effect. A study published online Jan. 26, 2015, in JAMA Internal Medicine linked daily anticholinergic use among older adults for three or more years to an increased risk for developing dementia and Alzheimer's disease.

The study didn't prove that anticholinergics cause dementia; it only found an association between people who take the medications and people who develop dementia. Nevertheless, the researchers suggest that doctors avoid prescribing anticholinergics when possible, or at least limiting the medications to the lowest doses possible. If you're taking an anticholinergic, talk to your doctor about the risks the medication poses, including the risk of falls as a result of confusion.

When are opioids safe to take?

Opioids are commonly used to control acute, intense pain. Meditation, yoga, and acupuncture may help control pain when tapering off opioids.

Although these powerful pain relievers can be addictive, opioids are safe for most people when used properly.

Common drugs linked to dementia

Medications called anticholinergics are used to treat a host of conditions—overactive bladder, depression, allergies, and Parkinson's disease. They usually aren't recommended for older adults because one of the most common side effects is confusion and difficulty reasoning. Early studies have also indicated that long-term anticholinergic use is associated with an increased risk of dementia, and a recent study by researchers at the University of Washington adds more evidence to support that connection. The results were published online Jan. 26, 2015, by JAMA Internal Medicine.

The researchers tracked almost 3,500 men and women ages 65 and older who were free of dementia. When they matched prescription data for the previous 10 years with the participants' health outcomes, they determined that using anticholinergics was associated with an increased risk of developing dementia. Moreover, dementia risk increased with the dosage of the drugs and the length of time they were used. While people who had taken these drugs daily for the equivalent of three months had no increase in risk, those who had used them for over three years had a 54% greater risk than nonusers.

A stable weight may reduce fracture risk

A study published in the Jan. 27, 2015, issue of The BMJ challenges the longstanding notion that weight gain protects against postmenopausal fractures. Data from the Women's Health Initiative (WHI) indicate that weight gain, as well as weight loss, is associated with increased risk of fractures in postmenopausal women. The analysis also suggested that which bones were most likely to break depended on whether women have gained or lost weight.

WHI researchers analyzed data on over 120,000 healthy postmenopausal women ages 50 to 79 at the start of the study. Each year, participants were weighed and asked to report fractures of their arms, legs, hip, pelvis, and spine.

Boost the power of your breakfast cereal

Image: Thinkstock

One serving each of whole-grain cereal, low-fat milk, and fruit meet the requirements for a healthy breakfast.

Learn which ingredients will give your day a healthy start.

Grocery store shelves are filled with dozens of breakfast cereals all promising important health benefits. But how do you know if you're getting what you need? "Labels and marketing promises on boxes can be confusing. It's best to go cereal shopping with a plan," says Kathy McManus, director of the Department of Nutrition at Harvard-affiliated Brigham and Women's Hospital. She advises that you complement cereal with milk for protein and calcium and with fresh fruit for natural sweetness and some fiber. Don't worry if the cereal is organic or not. But do read ingredient lists carefully, and aim for the following markers of good nutrition.

Tips to help the medicine go down

Adding medications to foods and trying new swallowing techniques can help.

Swallowing pills can be difficult and downright unpleasant. It causes one in three people to gag, vomit, or choke. That may keep people from sticking to their medication routines, which can make them sicker. "We often see people who can swallow food and liquid just fine, but have difficulty with pills," says Denise Ambrosi, director of the Speech-Language Pathology Department at Harvard-affiliated Spaulding Rehabilitation Hospital.

A wake-up call on coffee

This popular beverage may have benefits beyond a morning buzz. But be careful with your add-ins.

Coffee drinkers around the world savor the bitter brew on a daily basis. But are there any grounds for concern regarding coffee's effects on the heart? On the contrary: the case for drinking coffee seems to be growing. Straight coffee—minus the cream and sugar—is a nearly calorie-free beverage brimming with antioxidants. It might ease artery-damaging inflammation and may deliver a substance that helps the body regulate blood sugar.

"The evidence for the benefits of coffee consumption is even more convincing than it was five years ago, especially when it comes to preventing type 2 diabetes and reducing risk of heart disease and stroke," says Dr. Frank Hu, professor of nutrition and epidemiology at the Harvard School of Public Health.

Having a big belly puts your heart in danger

Cutting back on carbohydrates can help shrink a bulging midriff.

Pants getting a little snug? It's not just you: Americans' waistlines have ballooned over the past decade or so, to an average of just under 40 inches for men and almost 38 inches for women, according to a large federal study.

A new way to "beet" high blood pressure?

 

 

 

 

Images: Thinkstock

Beets rarely rank high on anyone's list of most-loved vegetables. But here's a reason to give these ruby-red roots another try: beet juice may help lower blood pressure, according to a study in the February 2015 Hypertension.

Beets contain naturally high levels of nitrates, which your digestive system converts into nitric oxide. This compound relaxes and widens blood vessels, which, in turn, lowers blood pressure.

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