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Easing the ache

Osteoarthritis pain can be debilitating. Strategies can help get you moving again.

Pain from osteoarthritis is more than just a nuisance. Knee pain, in particular, can not only keep people from exercising, but also have a chilling effect on their ability to participate in social activities, especially those that involve walking or traveling, says Elena Losina, the Robert W. Lovett Professor of Orthopedic Surgery at Harvard Medical School and co-director of the Orthopaedic and Arthritis Center for Outcomes Research at Brigham and Women's Hospital.

"In fact, the quality of life of a person with persistent pain due to knee osteoarthritis is similar to quality of life in women with metastatic breast cancer controlled by therapy," she says.

How can I treat painful night leg cramps?

On call

Q. I occasionally get an excruciating leg cramp that wakes me from sleep. What causes leg cramps, and how can I prevent them?

A. Although nocturnal leg cramps can strike people at any time of life, they become more frequent with age. Among people older than age 50, about half report having leg cramps, a third say they are awakened at night by them, and 15% report having cramps about once per week.

Getting a leg up on sciatica

Sciatica's (pronounced sigh-AT-eh-ka) hallmarks are pain and numbness that radiates down the leg, often below the knee. In nine out of 10 cases, sciatica is caused by a displaced disk in the lower spine.

The best medicine is often patience — with some stoicism mixed in — because the pain often goes away, even if the problem disk does not. Researchers have found that the pain usually improves within a month.

Which painkiller is safest for you?

It's more important than ever to consider your particular health risks before popping a nonprescription pain reliever.

Have a headache, muscle strain, or maybe arthritis pain? Don't reach for just any over-the-counter (OTC) remedy. Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin), naproxen (Aleve), and aspirin are commonly used OTC painkillers. So is acetaminophen (Tylenol). For decades, these drugs were thought to be entirely safe — justifying the ability to purchase them without a doctor's prescription.

But the thinking on OTC painkillers has changed now that we know more about their risks. And it's especially important to navigate these medications with care. Here are guidelines to help you narrow the options.

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