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Mind & Mood Archive

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Undoing the harm: Tapering down from high-dose opioids

The CDC’s Guideline on Prescribing Opioids for Chronic Pain helps doctors and patients manage treatment at safe levels and avoid dependence. Any plan to taper medication dosage should be personalized to the patient’s needs.

Do we lose memories forever?

Ask the doctor

Q. When we lose memories, do we lose them forever? A friend told me they may still be in our brains.

A. Our memories are stored inside nerve cells in our brains, often in multiple cells that communicate with each other. Each nerve cell looks a little like a tree, with a trunk, branches and, ultimately, little "twigs" (called spines). The spines of one cell communicate with those of another cell by releasing chemicals.

Using mind over matter to help treat chronic pain

News briefs

Many people use psychological techniques to help them cope with chronic pain. But which approach is best? A study published Jan. 31, 2019, in the journal Evidence-Based Mental Health offers insight. Researchers analyzed 21 randomized studies focusing on the effect of either cognitive behavioral therapy (CBT), to redirect pain-related thoughts and behaviors, or mindfulness-based stress reduction (MBSR), combining yoga and meditation to build awareness and acceptance of moment-to-moment experiences (including pain). The result: There was no clear winner. Both approaches reduced pain and depression and improved physical functioning compared with usual care or no care. The authors say the findings are important, since CBT is considered the go-to psychological technique for chronic pain. But MBSR should be considered as an additional tool, they suggest. Want to try it? Many hospitals, universities, and meditation centers offer MBSR programs. You can also search for MBSR videos and classes online.

More evidence that exercise can boost mood

Running for 15 minutes a day or walking for an hour reduces the risk of major depression, according to a recent study.

It may be possible to outrun depression, according to a study published online January 23 by JAMA Psychiatry.

"We saw a 26% decrease in odds for becoming depressed for each major increase in objectively measured physical activity," says study author Karmel Choi, a clinical and research fellow at the Harvard T.H. Chan School of Public Health. "This increase in physical activity is what you might see on your activity tracker if you replaced 15 minutes of sitting with 15 minutes of running, or one hour of sitting with one hour of moderate activity like brisk walking."

Breathing lessons

Learning to "belly breathe" helps ease your body's response to stress and tension.

The average person takes between 17,000 and 23,000 breaths per day, but there is a good chance we don't always breathe the right way. Chalk it up to how we deal with stress.

"When we feel something as a threat, our fight-or-flight response automatically kicks in," says Dr. Katherine Rosa, with the Harvard-affiliated Benson-Henry Institute for Mind Body Medicine. "Our breathing becomes more rapid and shallow and our hearts beat faster, all of which prepares us to run away from the threat."

Questions & Answers: Does Accutane cause depression?

ARCHIVED CONTENT: As a service to our readers, Harvard Health Publishing provides access to our library of archived content. Please note the date each article was posted or last reviewed. No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician. 

Q. Does the acne drug, isotretinoin (Accutane), cause depression and suicide, or are psychiatric risks from the Accutane side effects exaggerated?

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