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Menopausal hormone therapy (MHT) Archive

Women's Health

Late-start hormone therapy: Safe or risky?

Published May 19, 2026

Guidelines recommend that women starting hormone therapy do so before age 60 and within 10 years of menopause onset. Starting later may raise the risks of heart attack, stroke, or dementia. Women who start hormone therapy at 70 or older face even greater cardiovascular risks.

Women's Health

FDA removes menopause hormone therapy black box warnings

Updated November 13, 2025

After an FDA panel was convened to review black box warnings on menopause hormone therapy, which includes both systemic and vaginal estrogen treatments, the FDA announced in November 2025 it would remove black box warnings from all hormone therapy products containing estrogen. Women considering hormone therapy should discuss their individual health risks with their doctor - such as a history of heart attack or stroke, a blood clot in the legs or lungs, hormone-sensitive cancer, active liver disease, and overall breast cancer and cardiovascular risks.

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