Medications Archive

Certain medications can leave people more vulnerable to heat-related effects or the sun's rays. The medications can raise the risk of dehydration, make people sweat too much or too little, impair the body's ability to regulate temperature, or raise the risk of getting a bad sunburn. In addition, higher temperatures may damage some medicines, including diuretics, blood pressure drugs, some antidepressants, thyroid replacement hormones, and some over-the-counter antihistamines.

In the last few years, the prescribing rate for zolpidem, a popular sleeping pill, has been declining in favor of the "off-label" use of an antidepressant called trazodone, which is known for its ability to make people drowsy. But doctors are concerned that trazodone hasn't been well studied for insomnia, it is not FDA-approved to treat the condition, and there are sparse data showing that it is safe or that it works for patients with insomnia. Experts advise choosing medications based on a patient's specific needs, not a trend.

In its 2025 guidelines for treating restless legs syndrome (RLS), the American Academy of Sleep Medicine stopped recommending the long-term use of dopamine agonist drugs, since they can eventually make RLS symptoms worse. Instead, the guidelines strongly recommend another class of medications as the first-line treatment: alpha-2-delta ligands, such as gabapentin (Neurontin), gabapentin enacarbil (Horizant), and pregabalin (Lyrica). Alpha-2-delta ligands do not make RLS symptoms worse.

A 2025 analysis suggested that GLP-1 medications used for diabetes and weight loss are associated with lower risks for an array of conditions, but that they increase risks for several others.

Direct-to-consumer (DTC) drug ads promoting treatments for arthritis, cancer, heartburn, psoriasis, flagging memory, and more are all everywhere you look. All too often, the information shared is incomplete, biased, or confusing––here's what to watch out for and how to get the whole story when considering treatment options. 

In a 2025 study of 1,800 patients undergoing dental surgery, a combination of two over-the-counter pain relievers was more effective and produced fewer side effects than prescription opioids for treating postsurgical pain.

The FDA added a boxed warning in December 2024 to fezolinetant (Veozah), a nonhormonal drug that reduces hot flashes and night sweats in menopausal women. The drug may cause rare but serious liver injury.

When debating whether to use a pain pill or a pain patch to treat discomfort, it helps to note the main differences between the two. Pain pills are the first choice to relieve sudden or immediate pain. For more persistent or chronic pain, patches can be used alone or combined with certain pain pills. Before using multiple therapies at the same time, check with your doctor or pharmacist for safety.

The troubling symptoms of prostatitis, or inflammation of the prostate, accounts for roughly two million doctor visits every year. Fortunately, research advances are leading to some encouraging developments for men suffering from this condition.