Medical Tests & Procedures Archive

Coronary computed tomography angiography (CCTA) creates a 3D image of the heart and its blood vessels, revealing both obstructive and nonobstructive plaque. Most heart attacks occur when smaller, nonobstructive plaques rupture and form a clot that triggers a heart attack. Used to assess people with stable angina, CCTA may prevent heart attacks by improving how cardiologists find and treat heart disease.

Nearly one in five hospitalized adults is harmed or dies each year due to a diagnostic error. Diagnostic errors include a delay in diagnosis, a wrong diagnosis, or unclear communication about a diagnosis. Tricky-to-diagnose conditions include pneumonia, heart attack, stroke, sepsis, blood clots, and lung cancer. Women, minorities, and older adults may be more vulnerable to diagnostic mistakes. People can lower their risks of diagnostic errors by telling the doctor about their medications, taking a trusted companion to appointments, and seeking second opinions in cases of doubt.

The approach to certain blood tests appears to be shifting. Doctors might stop ordering routine vitamin D screenings for healthy people younger than 75; they might order a one-time combination of lipoprotein(a), C-reactive protein, and LDL (bad) cholesterol tests as a way to predict future heart problems; and they might rely less on standard ranges designated as "normal" in a complete blood count (CBC) test, and instead focus more on comparing someone's latest CBC results to previous CBC tests.

Most people don't need to fast before a lipid test because the difference between LDL cholesterol values when fasting or not fasting is very small. But people who have had high triglyceride levels should fast prior to the test.

Leg pain may be caused by deep-vein thrombosis (DVT), a blood clot that forms in a deep vein, usually in the leg. Left untreated, the clot may break off, travel to the lungs, and cause blockage in a lung artery, known as pulmonary embolism (PE), which can be life threatening. Diagnosis of DVT and PE may include a review of symptoms, a D-dimer blood test, a leg ultrasound, or a chest CT scan. Both conditions are most often treated with direct-acting oral anticoagulants.

People who follow a healthy lifestyle can still have the early stages of coronary artery disease (CAD), the most common type of heart disease. There are many ways people can find out if they have CAD. This includes paying attention to whether exercise causes discomfort, doing a 10-year heart risk assessment, and seeing their doctor for diagnostic testing, such as a coronary artery calcium scan, a resting electrocardiogram, a walking stress test, or an echocardiogram. A doctor uses this information to determine the best treatment path.

High levels of Lp(a)—a fatty particle similar to LDL cholesterol—may double or triple a person's risk of a heart attack. About one in five adults may have elevated levels, which also raises the risk of stroke and aortic stenosis. Unlike LDL, which rises with age and is influenced by diet and exercise, Lp(a) remains largely constant over a person's lifetime, so a one-time test suffices for screening. Lp(a) testing is becoming more common now that five promising new Lp(a) therapies are in development.

After a heart attack or stent placement, people typically take a combination of aspirin and another antiplatelet drug. After one year, the new standard practice is to stop the aspirin, in contrast to the previous practice of stopping the other drug.

Roughly one in six men will be diagnosed with prostate cancer at some point in their lives, but these cancers usually aren't life-threatening. The least risky form of the disease occurs frequently with age, will not metastasize to other parts of the body, and it doesn't require any immediate treatment. So, should it even be called cancer?