Heart Medications Archive

Aspirin therapy can help prevent a second heart attack and stroke, but for otherwise healthy older men, its use depends on their 10-year risk for a heart attack or stroke as determined by their doctor. 

In a large, long-term clinical trial, people taking the diuretic chlorthalidone had significantly fewer hip fractures than those taking the calcium-channel blocker amlodipine or the ACE inhibitor lisinopril.

Most people with atrial fibrillation take anti-clotting drugs to prevent strokes. For those who cannot take these drugs because of a high risk of bleeding, a tiny, basket-like device implanted in the part of the heart that traps clots may be an alternative. 

Despite new research, the answer is unclear. Use caution when taking any pain medication on a routine basis.

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People with aching joints from arthritis—which affects nearly one in four adults—often rely on drugs known as NSAIDs to ease the pain of this often-debilitating condition. These popular medications also relieve headaches, cool fevers, and dampen inflammation. But with the exception of aspirin, most NSAIDs pose a risk to the cardiovascular system, notes Harvard professor Dr. Elliott Antman, a cardiologist at Brigham and Women's Hospital.

"Taking NSAIDs routinely over a long time period can raise the risk of blood clots, increase blood pressure, and accelerate cardiovascular disease," says Dr. Antman. While the danger is greatest in people with heart disease, it's also present in people without any signs of the disease.

Ask the doctor

Q. Should I take aspirin if I think I'm having a heart attack, and what kind of aspirin should I take?

A. First, what symptoms indicate you might be having a heart attack? The main symptom is a squeezing, tight sensation in the middle of the chest that can travel up into the jaw and shoulders, and even down the left arm. Along with the pain you may begin to sweat and to feel weak, like you might pass out, and be short of breath. While other conditions besides a heart at-tack can cause similar symptoms, you need to take such symptoms very seriously. First, call 911.

Tracking your progress and symptoms can help you discern the difference.

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You probably know that when you take a medication, you need to tell your doctor about any side effects that develop. But being aware of side effects can be challenging when you're older. "In many cases, the signs of aging are similar to side effects of medications," says Joanne Doyle Petrongolo, a pharmacist at Harvard-affiliated Massachusetts General Hospital.

Similarities

The fix

Certain cholesterol-lowering medications—namely, ezetimibe (Zetia) and drugs known as bile acid binders—also appear to be effective at lowering cholesterol and reducing the risk of serious cardiovascular events. 

Medications such as aspirin, statins, ACE inhibitors, and beta blockers are prescribed to certain patients to lower the chance of a first or repeat heart attack. New research shows that they also may reduce the severity of attacks that do occur.

Millions of older adults aren’t taking their blood pressure drugs as directed. Ways to combat adherence problems include asking a doctor for less expensive drugs, understanding what a medication is for, and reporting side effects. 

The discovery of 44 gene sites associated with high blood pressure may provide leads for developing new drugs to treat this common condition.