Digestive Health Archive

Groundbreaking cancer treatments continuously emerge from labs and research trials. Three Harvard oncologists share what stands out in their respective fields of prostate, lung, and colon cancer, the most common cancers among men. Examples include greater roles for immunotherapy, targeted therapy, and intensive hormonal treatments.

In recent years, treatment options for inflammatory bowel disease have expanded rapidly, with new types of drugs, new medications within existing classes, and new combinations of treatments for some patients.

Nearly half of all people with inflammatory bowel disease have symptoms that occur outside of the gastrointestinal tract. These conditions, known as extraintestinal manifestations (EIMs), can affect the musculoskeletal system, eyes, lungs, and other areas of the body.

Lung cancer kills about 130,000 Americans yearly, but only a tiny percentage of people eligible for low-dose CT lung cancer screening receive it. People qualify for lung cancer screening if they are 50 to 80 years old, have a substantial smoking history as measured in lifetime packs smoked, and currently smoke or quit within the past 15 years. Tens of thousands of lives might be saved each year if everyone who qualified underwent lung cancer screening, which can detect tumors when they are still small enough to be cured with surgery or radiation.

Everyone experiences acute (short-term) diarrhea at some time. The unpleasant experience often resolves on its own in a few days, but there are situations that require medical attention. Examples include bloody diarrhea, severe abdominal pain, a high fever, and episodes that continue for a week or longer. A medical consultation can help determine if diarrhea is related to a specific bacterium or parasite, a medication side effect, a food intolerance, or an inflammatory bowel disease.

Lactose intolerance can develop at any age, prompting gas, bloating, nausea, or diarrhea after people eat or drink dairy products. Secondary lactose intolerance can happen after the small intestine is jolted by surgery, illness, or injury.

Current guidelines for women under 65 with early-stage breast cancer recommend following lumpectomy with radiation therapy, but emerging research could expand the option of skipping radiation to some women as young as 55.

Palliative care is a medical specialty meant to help people during many different stages of health. Many people who might benefit from palliative care do not receive it; if more people understand it, more people can take advantage of it.

Proton-pump inhibitors are a commonly prescribed anti-acid medication, but new guidelines from the American Gastroenterological Association recommend that they should be taken at the lowest dose and shortest duration for the condition being treated.

Around menopause, a decline in estrogen can trigger low-grade inflammation that leads to unexpected symptoms from head to toe. Symptoms can affect the digestive tract, skin, joints, eyes, ears, and heart, among other areas. A 2022 study found that estrogen loss can even fuel the jaw pain known as temporomandibular disorder. A year or longer can pass before many women connect symptoms with menopause. Women can take lifestyle measures to lower inflammation, such as eating more fruits and vegetables, avoiding processed foods, and exercising.