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Antidepressants tied to weight gain

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 Image: © adamkaz/Getty Images

We're learning more about the link between weight gain and several major classes of antidepressants, such as selective serotonin reuptake inhibitors (SSRIs), like sertraline (Zoloft), and tricyclic antidepressants, such as amitriptyline (Elavil). Research has shown that putting on pounds is a possible short-term side effect of the medications. But a study published May 23, 2018, in The BMJ suggests that antidepressants are also associated with sustained weight gain. Researchers analyzed the health information of more than 300,000 people in the United Kingdom (average age 51) who'd had their weight and body mass index measured at doctor appointments between 2004 and 2014. About 18% had been prescribed antidepressants. During the study period, people who took antidepressants had a 21% higher risk for a 5% or greater weight gain, compared with people who didn't take antidepressants. The risk peaked in the second and third years. There was no evidence of weight gain after seven years. The study was observational and didn't prove that antidepressants cause weight gain. But researchers hope the findings will encourage people to talk to their doctors about weight gain as a possible side effect of antidepressants, and plan for potential and even delayed weight gain if they're using the medications.

Strengthen your mood with weight training

Performing resistance exercises could help ease symptoms of depression.

Pumping iron might inflate not only your muscles, but also your mood, says a study in published in the June issue of JAMA Psychiatry.

The study's authors came to this conclusion after examining the results of 33 randomized clinical trials involving more than 1,800 people. They found that people with mild to moderate depression who performed resistance training two or more days a week saw "significant" reductions in their symptoms, compared with people who did not. The findings also suggested that resistance exercises may be even more beneficial for those with more severe depressive symptoms.

Feeling young could signal a younger brain

In the journals

People who feel younger than their actual age also may have brains that age more slowly, suggests a small study published online June 7, 2018, by Frontiers in Aging Neuroscience.

Scientists took brain scans of 68 healthy older adults, ages 59 to 84, to measure the volume of gray matter in various regions. The participants then answered surveys to determine if they felt older or younger than their age and to measure their cognitive abilities and perceptions of overall health.

Your heart’s desire: A daily practice to relieve stress

Every day, carve out a little time to release your worries and relax your mind. It may counteract the heart-damaging effects of stress.


 Image: © Photodjo/Getty Images

Stress is an inevitable part of life. People often fret over day-to-day hassles such as traffic jams and unpaid bills, not to mention the relentless news about natural disasters and political crises. Many are also coping with the added anguish of divorce, illness, or death within their families.

All of these so-called psychosocial stresses first take hold in your mind. But the effects spread throughout your brain and body. Sometimes, you can even feel it: your heart pounds, you breathe faster, and your muscles tense. However, chronic stress also has more insidious physical effects that can harm your heart (see "Stress and your cardiovascular system").

Does a virus cause Alzheimer’s?

Ask the doctor


 Image: © Dr_Microbe/Getty Images

Q. I know that some viruses live permanently inside us, but only make trouble now and then. I even heard recently that they might be a cause of Alzheimer's disease. Why do they sometimes cause disease, and can we keep that from happening?

A. We live all of our lives with various microorganisms on us and inside us. One example is the herpes family of viruses. Out of more than a hundred herpesviruses, there are nine that infect humans. Once we get infected with these viruses — usually early in life — they remain with us, "asleep" inside some of our cells. But periodically, they "wake up" (reactivate), start producing multiple copies of themselves, and infect other cells. That's what's happening when a cold sore suddenly forms on your lip.

Depression and illness: Chicken or egg?

Image: iStock

When depression strikes, doctors usually probe what's going on in the mind and brain first. But it's also important to check what's going on in the body, since certain medical problems are linked to mood disturbances. In fact, medical illnesses — and medication side effects — may be behind nearly 10% to 15% of all cases of depression.

It's not uncommon for a physical illness to trigger depression. Up to half of heart attack survivors and those with cancer report feeling blue, and many are diagnosed with depression. Many people who have diabetes, Parkinson's, or other chronic conditions become depressed.

Writing as an antidote to loneliness

Because social connections are vital to human development and health, and writing is a way to form or strengthen a sense of connection to others, the creative expression of writing has been found to improve health and boost healthy emotions.

Tips to cope when it’s time to downsize

Asking for help from friends and family and then engaging with your new community will get you through the transition.


 Image: © IPGGutenbergUKLtd/Getty Images

Downsizing from a large home to a smaller one is a fact of life for many older adults. The reason may be finances, health issues, or a desire to simplify your lifestyle. But making the transition can bring a host of emotions: sadness, grief, stress, or anxiety.

Understanding the triggers for these feelings and using strategies to navigate them may not change how you feel, but it may help the downsizing process go more smoothly so you can focus on your next chapter.

Tips to cope when it’s time to downsize

Asking for help from friends and family and then engaging with your new community will get you through the transition.


 Image: © IPGGutenbergUKLtd/Getty Images

Downsizing from a large home to a smaller one is a fact of life for many older adults. The reason may be finances, health issues, or a desire to simplify your lifestyle. But making the transition can bring a host of emotions: sadness, grief, stress, or anxiety.

Understanding the triggers for these feelings and using strategies to navigate them may not change how you feel, but it may help the downsizing process go more smoothly so you can focus on your next chapter.

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