Memory Archive

Research we're watching

Can emotional stress harm your bones? A new study found an association between stressful social relationships and bone problems in women. The study, which was published online July 9 by the Journal of Epidemiology & Community Health, found that women who reported high levels of social stress had lower bone density six years later. The study looked at more than 11,000 postmenopausal women. At the time of enrollment, the women filled out a questionnaire that asked them to rate their social stress levels and had their bone density measured both at enrollment and six years later at a follow-up appointment. Women who had reported high levels of stress at the initial interview showed a bigger decline in bone density at the follow-up compared with women who'd initially reported lower stress levels. This was true even after the researchers adjusted for other factors that may affect bone health, such as age, weight, smoking, alcohol use, and education, among others. The authors speculated that stress may harm bone health because stress leads to higher blood cortisol levels, a well-established reason for lower bone density. Further study is needed to understand and confirm the results.

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Clinical trials for drugs to stop or slow the progression of dementia have not been successful. A recent study attempted to determine how much influence, if any, genetic and lifestyle factors may have on the development of dementia.

In the journals

Gingivitis (gum disease) has been linked to a higher risk of heart disease, but a recent study says that the bacteria that cause gingivitis also may be connected to Alzheimer's disease. The study was published Jan. 23, 2019, in Science Advances.

Scientists have previously found that this species of bacteria, called Porphyromonas gingivalis, can move from the mouth to the brain. Once in the brain, the bacteria release enzymes called gingipains that can destroy nerve cells, which in turn can lead to memory loss and eventually Alzheimer's.

Study shows an association between a strong sense of purpose in life and a lower risk of death from cardiovascular problems and blood conditions.

If you believe your life has meaning, it could potentially be longer, says a new study published online May 24 by JAMA Network Open.

Study authors found that among a group of nearly 7,000 adults over age 50, those who scored highest on a scale that measured "life purpose" were less likely to die during the study period, and also less likely to die during the same period from heart, circulatory, or blood conditions, compared with those who scored lower.

Sedative effects of drinking can also initiate other physical responses in the body

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Many people think that a little nightcap will help them sleep soundly through the night. Although alcohol's sedative effects can make you drowsy, they also have other effects that can interfere with quality sleep.

Several hours after that nightcap, the alcohol raises the body's level of epinephrine, a stress hormone that increases the heart rate and generally stimulates the body, which can result in nighttime awakenings. Indeed, alcohol may account for 10% of cases of persistent insomnia. Alcohol also relaxes throat muscles, and this relaxation can worsen sleep-related breathing problems and contribute to sleep apnea. What's more, alcohol may increase the need to urinate during the night — just another way in which it can disrupt sleep.

Brain-based devices claim to offer all kinds of enhancements and improvements, but how can consumers interested in such a device separate legitimate science from mere hype?

Research we're watching

The World Health Organization has some advice for people who want to reduce their risk of dementia — pay attention to your overall health. Specifically, the organization's new guidelines recommend regular exercise, maintaining a healthy weight, regulating blood sugar levels, and keeping cholesterol within recommended limits.

Experts also recommend giving up unhealthy habits, including drinking and smoking. In short, strategies that you already know are good for your heart and overall health are also good for your brain. Preventing dementia is a focus because it has become a growing health problem, which affects some 50 million people around the world. The WHO estimates that nearly 10 million people each year develop the condition.

News briefs

Losing a loved one is never easy, and sometimes it can take years to grieve for a partner, parent, or child. That grief often comes with adverse health effects, such as stress, depression, insomnia, high blood pressure, and heart problems. But long-lasting grief doesn't come only from a family member's death, suggests a study published online April 4, 2019, by PLOS One. Researchers evaluated questionnaire responses from about 9,600 people who'd lost close friends and found this type of grief can last up to four years. Women in the study were particularly hard hit by loss of a close friend, experiencing more problems with mental, emotional, and social health than men. Study authors say the passing of a close friend should be considered a substantial experience that warrants help (like a support group) to minimize the negative effects of grief.

Our take: Grief of any kind poses a health risk, whether it's due to the loss of someone dear or a dramatic change in life, such as a job loss or a move to a new city. During such times, be especially vigilant about reporting disturbing new symptoms to your doctor.

Many conditions can affect your memory and thinking.

Dementia, Alzheimer's disease, mild cognitive impairment. These terms are often mentioned together to describe age-related memory loss. While they are linked in some ways, they are not necessarily the same, and they often affect people differently.

"Even though memory loss is more common as you age, it is not part of normal aging," says Dr. Gad Marshall, associate medical director of the Center for Alzheimer Research and Treatment at Harvard-affiliated Brigham and Women's Hospital. "Either sudden or gradual persistent changes in memory loss and mental lapses can be signs of more serious conditions."