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Poor sleep linked to dementia and ministrokes

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Poor sleep is linked to high blood pressure, diabetes, obesity, and heart disease. Now a study published in Neurology Dec. 10, 2014, suggests that people with conditions that rob them of oxygen and deep sleep are more likely to have changes in the brain that may lead to dementia. Researchers say conditions such as emphysema and sleep apnea reduce the amount of oxygen in the blood during sleep, which can lead to silent, undetectable "ministrokes." Researchers also found that people who spend less time in deep sleep, called slow-wave sleep, are more likely to have loss of brain cells than people who spend more time in slow-wave sleep. Slow-wave sleep is important in processing new memories and remembering facts. The researchers noted that past evidence has shown that using a continuous positive airway pressure (CPAP) machine for obstructive sleep apnea may improve cognition, even after dementia has developed. "Sleep quantity and quality are important to maintain optimal health and prevent disease," says sleep expert Dr. Lawrence Epstein, an instructor in medicine at Harvard Medical School. "By getting enough sleep, you ensure that you are getting all the types of sleep, which is necessary to maintain proper functioning." 

People with type 1 diabetes are living longer

Ninety years ago, type 1 diabetes was a death sentence: half of people who developed it died within two years; more than 90% were dead within five years. Thanks to the introduction of insulin therapy in 1922, and numerous advances since then, many people with type 1 diabetes now live into their 50s and beyond. But survival in this group still falls short of that among people without diabetes. A Scottish study published this week in JAMA shows that at the age of 20, individuals with type 1 diabetes on average lived 12 fewer years than 20-year-olds without it. A second study in the same issue of JAMA showed that people with type 1 diabetes with better blood sugar control lived longer than those with poorer blood sugar control.

Diabetes in midlife may hasten dementia in later life

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If you have diabetes or prediabetes and you need motivation to get your blood sugar under control, consider this: a study published Dec. 2, 2014, in Annals of Internal Medicine suggests that diabetes in midlife appears to age the mind at a faster rate in later life. Researchers analyzed changes in the thinking skills of more than 15,000 people during a 20-year period. The average age at the start of the study was 57. Twenty years later, among people with a history of diabetes, there was 19% more decline than expected. There were even declines, although smaller, among people with a high blood sugar condition known as prediabetes. "We know that over time, diabetes, like hypertension, will cause mini-strokes in the brain that will impair one's thinking and memory. This study strengthens the claim that addressing cardiovascular risk factors like diabetes early may prevent dementia in the future," says Dr. David Hsu, a psychiatrist in the Center for Alzheimer Research and Treatment at Harvard-affiliated Brigham and Women's Hospital. You can lower your blood sugar—and your risk of diabetes—by exercising, losing weight, and cutting back on refined grains and added sugars. 

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