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Should men over 70 with a family history still get a PSA test?

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By , Chief Medical Editor, Harvard Health Publishing; Editorial Advisory Board Member, Harvard Health Publishing
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A senior man in a consultation with his doctor in an exam room.

Q. I am 77. My brother died of prostate cancer. My doctor says I don't need PSA testing at my age. But because my brother died of the disease, my doctor will order the blood test if I want it. I'm not sure what to do. What is your advice?

A. There is no right or wrong answer. Your doctor is following a recommendation from the U.S. Preventive Services Task Force (USPSTF). The USPSTF still advises against routine testing for prostate cancer for men ages 70 and older. Recommendations like this help doctors make decisions, but they do not require what should be done in any specific situation.

However, the recommendations were last updated in 2018. Since then, research has found new diagnostic tests that significantly improve prostate cancer diagnosis starting with PSA. I suspect that many men over 70 will want to have PSA testing done.

By the way, the prostate-specific antigen blood test measures the amount of a chemical called prostate-specific antigen (PSA) in a man's blood.

There are three questions that I need answered before I can offer advice:

  1. Are you in good general health? (This means you have no health conditions that would likely cause you severe disability or death within the next 10 years.)
  2. Are you of African descent?
  3. If you are not of African descent, was your brother under age 60 when he was diagnosed with prostate cancer?

If your answer to question one is "No," you are not in good health, I would advise against your getting the PSA test. Why? Because someone in poor health is more likely to die from some cause other than prostate cancer. So there is little benefit in being tested and treated for prostate cancer.

If your answer to question one is "Yes," you are in good health, and your answer to question two or three is "Yes," then you should consider getting the PSA test.

Keep in mind that even if your brother died of prostate cancer that was diagnosed before he reached age 50 and/or you are of African ancestry, you are still more likely to die from some cause other than prostate cancer. But it is likely that your risk of aggressive prostate cancer is higher than average.

You should review all the possible complications of testing and prostate cancer treatment before getting the PSA test. If you decide you want the test, tell your doctor. If your doctor agrees (I would), he or she will also perform a digital rectal examination as part of the screening.

Image: © Maskot/Getty Images

About the Author

photo of Howard E. LeWine, MD

Howard E. LeWine, MD, Chief Medical Editor, Harvard Health Publishing; Editorial Advisory Board Member, Harvard Health Publishing

Dr. Howard LeWine is a practicing internist at Brigham and Women’s Hospital in Boston, Chief Medical Editor at Harvard Health Publishing, and editor in chief of Harvard Men’s Health Watch. See Full Bio
View all posts by Howard E. LeWine, MD
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