Ask the doctor: Can red yeast rice bring down cholesterol?

Published: August, 2013

Q. I am taking pravastatin for high cholesterol, but my numbers are still high. Should I try red yeast rice?

A. Red yeast rice, a fermented species of yeast called Monascus purpureus, has been used in traditional Chinese medicine for centuries. It contains a number of compounds called monacolins. Like the cholesterol-lowering statin drugs, monacolins hamper the production of cholesterol by inhibiting the enzyme HMG-CoA reductase, which makes LDL ("bad") cholesterol. One of the monacolins in red yeast rice extract is the active ingredient in lovastatin. In studies of people with high cholesterol, red yeast rice extract taken for two to three months lowers total and LDL cholesterol and triglycerides.

To continue reading this article, you must log in.
  • Research health conditions
  • Check your symptoms
  • Prepare for a doctor's visit or test
  • Find the best treatments and procedures for you
  • Explore options for better nutrition and exercise
Learn more about the many benefits and features of joining Harvard Health Online »