Medications Archive

Vascular dementia, which arises from longstanding, cumulative damage to small blood vessels in the brain, may cause or contribute to up to half of cases of dementia. The vessels may thicken or become blocked by blood clots, causing tiny strokes that damage specific parts of the brain important for various thinking abilities. Keeping blood pressure in the recommended range of 120/80 or lower is the best way to prevent vascular dementia.

Renewed research into the potential benefits of psychedelic drugs has led to interest in microdosing — taking a fraction of a regular dose. Many people believe that microdosing can help them, but the evidence from some recent studies is mixed.

Proton-pump inhibitors are a commonly prescribed anti-acid medication, but new guidelines from the American Gastroenterological Association recommend that they should be taken at the lowest dose and shortest duration for the condition being treated.

Geriatricians offer health guidance and treatment to adults 65 and older. The specialty centers on health concerns increasingly common with age, including falls, hearing loss, incontinence, memory problems, and the need to juggle multiple conditions and medications. Among other goals, geriatricians aim to optimize drug dosages and prevent medication overlap or dangerous side effects. They also coordinate each patient's care with other specialists who help manage chronic conditions. Geriatrician visits are typically longer than those with general practitioners.

Too much or too little potassium can harm the heart. Diet, medications, and kidney function can affect the body's potassium level. Dietary potassium helps keep blood pressure in a normal range, but most Americans don't consume enough of this mineral. However, people taking medications that raise potassium levels—which includes certain drugs to treat high blood pressure and heart failure—should avoid salt substitutes made with potassium chloride.

People with high triglyceride levels may be candidates for icosapent ethyl (Vascepa), a drug made from highly purified fish oil. It lowers triglycerides and, when taken with a statin, lowers the risk of heart attack, stroke, and death from cardiac causes.

The ongoing opioid epidemic in the US has been perceived as an issue that mostly affects white people in rural areas, but a recently published report from the CDC shows that the epidemic is now disproportionately affecting Black people.

Ketamine has been used for decades as an anesthetic, and in 2019 an inhaled version of it was approved by the FDA for treatment-resistant depression. But it is generally prescribed only when other treatments have not been effective.

People taking antidepressants may have many reasons for wanting to discontinue the drug. They may feel they no longer need the medication or decide they cannot tolerate side effects. A doctor should guide the process of tapering off antidepressants. The chance of depression recurrence is higher for people who take antidepressants long-term and stop abruptly. Withdrawal symptoms can make the tapering process uncomfortable, but it's generally not dangerous.

Most people with heart failure (or those at high risk for it) need several medications to treat their symptoms. New guidelines from the American College of Cardiology/American Heart Association have added another drug class to the treatment list: a group of diabetes drugs called sodium-glucose cotransporter-2 (SGLT-2) inhibitors. SGLT-2 inhibitors offer multiple benefits, such as helping to reduce swelling, lowering high blood pressure, assisting with weight loss, reducing complications associated with heart failure, and preventing hospitalization.