Heart Health Archive

A gene editing technique that permanently shuts down a cholesterol-raising protein called PCSK9 is being tested in heart attack survivors with an inherited form of high cholesterol. The one-time infusion contains tiny particles that contain the editing tools, which travel through the blood to the liver and changes the cells that produce the protein. If early data show the treatment to be safe and effective, the therapy potentially could be used in people who have "garden variety" high cholesterol.

A standing side leg raise helps strengthen muscles in the outer thighs, hips, and backside, which can improve the range of motion in the hips and improve stability.

A coronary artery calcium scan (often called a calcium scan) uses a special type of CT scan to look for calcium deposits in the lining of the heart's arteries. The results can help people decide whether to start taking a statin.

Running can boost cardiovascular fitness faster and better than walking, but this high-impact activity comes with a higher risk of injuries than walking. Beginning runners should start slow and alternate walking and running at first. Doing strength training and increasing mileage gradually may help. People who sustain minor injuries when running should rest for a few days and consult a physical therapist if the injury doesn't get better.

In addition to raising blood pressure, too much salt in the diet can have other detrimental effects on the heart, including damaging the inner layer of blood vessels and altering the body's hormonal and inflammatory response. Following the DASH diet, choosing lower-sodium versions of commonly eaten foods, and skipping the saltshaker can help people eat less salt. To boost flavor without salt, options include salt-free herb and spice blends, lemon or lime zest or juice, and flavored vinegars.

Coffee drinking has been linked to a lower risk of dying of heart disease. Coffee contains potent anti-inflammatory substances called polyphenols that may improve blood sugar control and help blood vessels contract and relax. Although the caffeine in coffee may help people control their weight, it can trigger a short-term rise in blood pressure and heart rate. Filtered coffee, which removes substances that may raise LDL (bad) cholesterol, appears to be a better option than unfiltered coffee.

Although uncommon, heart infections may trigger inflammation that can damage the heart. People should be aware of the risks and symptoms of the three main types: pericarditis (swelling and irritation of the protective, double-layered membrane that surrounds the heart, called the pericardium), myocarditis (inflammation in the middle, muscular layer of the heart), and endocarditis (inflammation that affects the heart’s inner lining or one or more of the heart’s valves).

In about half of all cases of heart failure, the heart’s muscles are thin and weak, so the heart can’t pump very well. In the other cases, the muscles are thick and stiff, which prevents the heart from relaxing normally to fill with blood.

Pulmonary hypertension affects the pulmonary arteries, which carry blood from the right side of the heart to the lungs. The vessels tighten, become stiff and thick, or develop blood clots. These changes reduce or block blood flow, raising pressure in the pulmonary arteries.

Exposure to microscopic particles called PM_2.5 in air pollution may increase a person’s risk of heart attack, stroke, and heart rhythm disorders. The tiny particles pass from the lungs into the bloodstream, triggering inflammation and other cell-damaging processes. Air pollution comes mainly from coal-fired power plants, industrial factories, and motor vehicles. To limit exposure, people should try to avoid exercising outdoors near busy roads or industrial areas.