Heart Disease Archive

Doctors concentrate on helping men lower their blood levels of low-density lipoprotein (LDL), or "bad" cholesterol, to lower their risk of cardiovascular disease. Lower HDL levels are associated with higher cardiovascular risk. This may be related to HDL's role in helping to remove excess cholesterol in arteries that can lead to plaque buildup and increase the risk of heart attacks and strokes. However, no specific therapies to raise HDL levels have improved outcomes.

The gut is home to trillions of microbes, collectively known as the gut microbiota, which help with digestion, manufacture certain nutrients, and release various substances that have wide-ranging health effects, including on cardiovascular health. As diet plays a significant role in the composition of the gut microbiota, people's diet can indirectly affect heart health. Following a plant-based diet that emphasizes less red meat and more fiber can support the gut and its heart-healthy benefits.

Sugary drinks—the biggest source of added sugar in the American diet—have been linked to higher levels of LDL cholesterol and other unhealthy fats in the bloodstream.

Microvascular disease refers to problems in the network of tiny blood vessels in the heart. Doctors suspect this condition in people who have angina (chest) pain with no evidence of blockages in the heart's larger arteries. In the most common form of microvascular disease, the inner walls of small arteries thicken, and the layer of cells closest to the blood lose their ability to expand and contract in response to the demand for increased blood flow, such as during exercise. In another form of the problem, vasospastic angina, muscles within the heart's arteries suddenly clamp down, causing a temporary spasm that blocks blood flow to heart muscle.

About 20% of people have high blood levels of lipoprotein(a)—Lp(a) for short—a fatty particle that's like the evil twin of the more familiar LDL ("bad") cholesterol. Elevated Lp(a) which can double or triple risk of a heart attack and raise stroke risk, and is linked to problems with the heart's aortic valve. With new treatments that can lower Lp(a) on the horizon, cardiologists are now testing more people for this biomarker, which is not included in standard cholesterol tests.

Side effects from both older and newer cancer therapies can affect the heart and blood vessels, possibly causing serious, sometimes life-threatening complications. People diagnosed with any type of cancer should ask their doctor whether their planned treatment might lead to cardiovascular problems. Those ages 65 and older and anyone with risk factors for heart disease (such as high blood pressure or diabetes) may want to request a referral to a cardio-oncologist. These specialists focus on preventing and managing cardiovascular problems in people who are undergoing (or have completed) treatment for cancer.

Vasculitis is characterized by inflammation of the blood vessels, including the arteries, veins, and capillaries. The resulting damage can narrow, weaken, or scar vessels that supply just one body part or many different organs.

A 2022 report predicts higher rates of cardiovascular disease (CVD)—heart disease, heart attack, heart failure, and stroke—over the next three decades. Older adults can lower their CVD risk by managing high blood pressure, high cholesterol, and excess weight. Also, they should follow the big three healthy-heart habits: a plant-based diet, sufficient amount of recommended exercise, and at least seven hours of sleep.

Using recreational drugs—including methamphetamine, opiates, cocaine, or cannabis—may increase a person's risk for atrial fibrillation.

A 2022 study found that older adults with sleep apnea who are hospitalized for cardiovascular disease are far less likely to be rehospitalized within 30 days if they consistently treat their apnea with CPAP therapy, which keeps the airway open during sleep.