Diseases & Conditions Archive

PrEP (pre-exposure prophylaxis) is a daily medication taken to prevent HIV infection. While multiple studies show PrEP is effective, relatively few of those who might benefit are taking it. Will a 10-year initiative to reduce rates of HIV and a new formulation of PrEP help?

Ask the doctors

Q. I've had endometriosis since I was in my 30s. I'm now approaching menopause. Will my symptoms get better or even go away after menopause?

A. Possibly, but not always. Endometriosis is a condition in which tissue that resembles the tissue that lines the uterus, called endometrial tissue, grows in other locations inside the body. Typically, it grows on structures and organs in the pelvis, such as the ovaries, fallopian tubes, bladder, or bowels. When a woman menstruates, this tissue behaves like the lining of the uterus and bleeds. But because this blood has no way to exit the body, it pools inside. This leads to pain, inflammation, and scarring.

Doctors say three recently approved migraine prevention drugs are helping people have fewer headaches.

For people with frequent, debilitating migraine headaches, 2018 brought encouraging news. The FDA approved three new medications — erenumab (Aimovig), fremanezumab (Ajovy), and galcanezumab (Emgality) — the first drugs designed specifically to prevent migraines and reduce their frequency, intensity, and duration.

It was a big development, since other medications used to stop migraines were created to control other conditions, such as seizures, depression, high blood pressure, or an irregular heartbeat. But their side effects (such as weight gain, dizziness, or fuzzy thinking) often cause people to skip treatment.

Some men with an enlarged prostate gland (benign prostatic hyperplasia, or BPH for short) eventually start to experience urinary incontinence, the involuntary discharge of urine. The incontinence can be related to overactive bladder, one of the changes in bladder function caused by BPH.

Normally, the brain says "time to go" when your bladder is only partially full. That gives you a fair warning to find a place to relieve yourself. When you decide to let go, a valve called the urinary sphincter opens to allow the bladder to drain. Muscles in the bladder wall squeeze inward to empty the storage tank.

Nerve damage might be causing everything from low blood pressure to gastrointestinal distress without your knowing it.

Doctors have long known peripheral neuropathy as a nerve condition that causes reduced sensation, tingling, weakness, or pain in the feet and hands. But those symptoms may be just the tip of the iceberg. Doctors are now learning that neuropathy can cause many more problems.

What is peripheral neuropathy?

Peripheral neuropathy refers to damage to the peripheral nerves throughout the body. These nerves carry messages to and from the brain.

Research we're watching

Rabies infections are extremely rare in the United States, with only approximately one to three cases seen each year. That number has dropped significantly since the 1930s and 40s when there were 30 to 50 cases during the average year. But when they do occur, they're typically transmitted by infected bats. According to a new report by the CDC, the majority of people who have died from rabies in the United States were infected through contact with a bat. This is the case even though bats represent only one-third of the 5,000 rabid animals typically seen in the United States each year. The second most common source for rabies infections in Americans is rabid dogs encountered when people are traveling overseas.

To prevent exposure to rabies, be certain to let your doctor know if you are scratched or bitten by a bat, or if you awaken with one flying around your house or bedroom, says the CDC. If you are exposed to rabies, your doctor can administer a series of shots (known as post-exposure prophylaxis) before you develop symptoms, which can prevent you from developing a rabies infection, which is almost always fatal. If you are traveling outside the United States, be aware that dogs may carry the infection.

Ask the doctors

Q. I understand that shingles is caused by a virus. Does that mean that shingles is contagious?

A. Yes and no. If you had chickenpox when you were a child, you are at risk for shingles. Shingles occurs when the varicella-zoster virus that caused your chickenpox re-emerges after lying dormant in your nerve cells from the time of your original illness. When this occurs, you are contagious, but you can't give someone shingles. You can, however, infect people with chickenpox if they haven't been exposed to the virus in the past and haven't been vaccinated against it. For this reason, it's important to take precautions, particularly if you are close to someone who has a weakened immune system.