Diseases & Conditions Archive

In the journals

Scientists continue to explore the health benefits versus risks of aspirin therapy. One new analysis suggests that taking aspirin may protect against several types of digestive tract cancers. The results were published online April 1, 2020, by Annals of Oncology.

Researchers examined 113 observational studies of cancer in the general population. They found that individuals who took aspirin regularly — at least one or two tablets a week — had significantly lower rates of cancers of the bowel, stomach, gallbladder, esophagus, pancreas, and liver, compared with people who did not take aspirin.

Lifestyle improvements, such as quitting smoking and exercising more, can reduce your risk of a stroke.

A stroke may seem like a sudden, uncontrollable event — a lightning strike out of the blue. But in reality, stroke risk often builds over time, and many strokes are preventable. A study published in the May 2020 issue of Stroke found not only that lifestyle changes can help you head off a potential stroke, but also that you can still reduce your risk even if you don't make these changes until later in life.

"What is novel about our study is that we found that even in middle-aged women, changing lifestyle has a large effect on preventing stroke," says Dr. Goodarz Danaei, senior author of the study and the Bernard Lown Associate Professor of Cardiovascular Health at the Harvard T.H. Chan School of Public Health. "Even in the sixth decade of life, lifestyle changes can still prevent up to a quarter of all strokes." The average age in women for a first stroke is 75.

How maintaining a healthy weight and other lifestyle habits can help prevent this common heart rhythm disorder.

During a bout of atrial fibrillation, your heart may beat so rapidly, it may feel as though it's going to explode out of your chest. Commonly known as afib, this heart rhythm problem can leave you breathless and lightheaded—or cause no symptoms at all. About 9% of people ages 65 and older have afib, which raises the risk of stroke and other heart-related problems. But there are ways to lower your odds of developing afib—or to reduce its impact if you already have the condition.

Lessen your load

By far, the most important step you can take is to attain and stay at a healthy weight. "We have good evidence from multiple studies showing that people who are overweight have a higher risk of afib than people who are at a healthy weight," says Harvard professor of medicine Dr. Christine Albert, former director of the Center for Arrhythmia Prevention at Brigham and Women's Hospital. And the more you weigh, the higher your risk: people who are overweight have a 20% to 25% higher risk, whereas those who are obese (a body mass index, or BMI, of 30 or higher) have a 60% higher risk.

Tennis elbow is the common term for lateral epicondylitis, an inflammatory condition of the tendon that connects the extensor muscles of the lower arm to a bony prominence on the outside of the elbow called the lateral epicondyle. The condition causes pain at the point where the tendon attaches to the epicondyle. The pain may radiate to the forearm and wrist, and in severe cases, grip strength may lessen. It can become difficult to perform simple actions like lifting a cup, turning a key, or shaking hands.

As many as half of all people who play racket sports have the condition, but most people who have tennis elbow didn't acquire it by playing tennis, squash, or racquetball. It can result from any activity that involves twisting or gripping motions in which the forearm muscles are repeatedly contracted against resistance, such as pruning bushes or pulling weeds, using a screwdriver, or playing a violin. Tennis elbow is an occupational hazard for professional gardeners, dentists, and carpenters.

Research we're watching

An increasing number of Americans have a blood abnormality that indicates autoimmunity, which means their immune system has created antibodies that could work against the body's own cells, according to a study published April 7, 2020, in Arthritis and Rheumatology. Autoimmunity can lead to autoimmune diseases such as rheumatoid arthritis or lupus, although the study authors said they didn't look to see whether the prevalence of diagnosed autoimmune diseases also rose during the same period of time.

The researchers found a rise over two decades in the number of people who had positive antinuclear antibody (ANA) blood tests, a signal of autoimmunity. They used blood samples taken from 14,211 people ages 12 and older, as part of the U.S. National Health and Nutrition Examination Survey. In samples taken in the period 1988 to 1991, ANA prevalence was 11%. It rose slightly to 11.5% for the 1999–2004 time period, and to 15.9% in the 2011–2012 period. Comparing differences in gender, race and age, the largest increases in positive ANA tests occurred in men, non-Hispanic whites, adolescents, and adults ages 50 and older.

On call

Q. I occasionally get an excruciating leg cramp that wakes me from sleep. What causes leg cramps, and how can I prevent them?

A. Although nocturnal leg cramps can strike people at any time of life, they become more frequent with age. Among people older than age 50, about half report having leg cramps, a third say they are awakened at night by them, and 15% report having cramps about once per week.

Do you struggle with decisions? These strategies can help you make good choices more efficiently.

We make countless choices every day. Most are the mundane variety: what to eat, what to wear, what movie to watch. But often our decisions (or lack thereof) have a significant impact on our well-being.

Poor decision making is often a consequence of natural cognitive decline. This can cloud people's judgment about what is the right course of action or make it harder to weigh multiple options. The result is that people make questionable choices, or they feel overwhelmed and don't make any decision, which is sometimes even worse.

Men need to manage their bone health as much as women do.

Most people think of osteoporosis as a women-only health problem, but older men also need protection from this bone-weakening disease.

About one in four men older than 50 will break a bone because of osteoporosis during his lifetime, according to the National Osteoporosis Foundation. And research has found that compared with women, older men are more likely to die following a fracture related to osteoporosis.

If you haven't made a video call yet, give it a try to fight isolation.

When much of the world began lockdowns to battle coronavirus in March 2020, many people turned to video calls to fight off the loneliness that often accompanies social isolation. Tech companies reported that the use of video calls for socializing surged by as much as 80%, enabling people to "see" family and friends. But it doesn't take a lockdown to warrant the use of this technology.

The epidemic of loneliness and isolation

Loneliness affects more than a third of older Americans. Another third of older adults feel isolated: they may be living alone, lack transportation, or live far from loved ones. Or they may have outlived a spouse or friends.

Ask the doctor

Q. I know doctors and scientists are very busy dealing with COVID-19. Is the need to care for, and do research on, COVID-19 affecting the care of and research on other important diseases?

A. You're right: the COVID-19 pandemic has consumed and disrupted medical care and medical research in the United States and around the world.