Diet & Weight Loss Archive

Semaglutide, a GLP-1 agonist used to treat diabetes and obesity, may also help people with metabolic dysfunction–associated steatohepatitis, a severe stage of fatty liver disease, suggests a 2025 study.

A 2025 research review found that healthy adults who paired exercise with time-restricted eating lost more fat than participants who didn’t restrict their eating window—without sacrificing lean muscle tissue.

Metabolic syndrome is defined as having at least three of the following: abdominal obesity, high blood triglyceride levels, high blood pressure, high blood sugar levels, and low HDL cholesterol levels. The condition significantly increases the risk for cardiovascular disease, diabetes, kidney disease, fatty liver disease, and sleep apnea. While each factor is problematic, the main driver is abdominal obesity, from visceral fat surrounding internal organs. The best way to reduce visceral fat is aerobic exercise, strength training, and a plant-based diet.

A 2025 study found that a pill version of the drug semaglutide, marketed as Rybelsus, can lower the risk for serious heart problems in people who have diabetes as well as cardiovascular disease, kidney disease, or both.

In a 2025 study, researchers estimated that fewer than four emergency department visits attributed to semaglutide (Ozempic, Wegovy) occurred for every 1,000 patients taking the drug in 2022 and 2023. Most of the visits were related to gastrointestinal problems.

A randomized controlled trial published in 2025 found that people who followed a 4:3 intermittent fasting plan for one year, eating only 20% of their usual calories on three fasting days per week, lost more weight than people who were on a calorie-restricted diet.

Cushing's is marked by elevated blood levels of the hormone cortisol. Far more common in women, the condition is categorized as a disease or syndrome based on what factors trigger it, which can include using corticosteroids or having a tumor on the brain's pituitary gland or elsewhere. Symptoms include a swollen face, excess belly weight, fatigue, a fatty hump between the shoulders, stretch marks, easy bruising, and slow wound healing. Cushing's can also lead to health problems such as cardiovascular disease, bone loss, and diabetes.

A 2025 review of 10 randomized controlled trials (involving about 300 people) found that those who took part in two or three one-hour water aerobics classes weekly for at least 10 weeks lost up to 6 pounds and trimmed their waists by about an inch.

When blood pressure remains high despite treatment, making certain lifestyle changes can help. Examples include reducing dietary sodium and increasing dietary potassium, losing weight, limiting alcohol intake to no more than one drink per day, exercising (doing aerobics and strength training), using tools that improve medication adherence (such as an automatic pill dispenser, a medication diary, a smartphone alarm, or a reminder app), quitting smoking, getting more sleep, managing stress, and reducing caffeine intake.