Blood Pressure Archive

A 2025 suggests that an experimental drug called lorundrostat may be an effective add-on therapy for high blood pressure that has not responded to medication. The drug works by reducing aldosterone, a hormone that helps regulate blood pressure.

Increasing potassium levels while lowering sodium may be more effective in lowering high blood pressure than reducing dietary salt alone, particularly for men, according to a 2025 study.

Metabolic syndrome is defined as having at least three of the following: abdominal obesity, high blood triglyceride levels, high blood pressure, high blood sugar levels, and low HDL cholesterol levels. The condition significantly increases the risk for cardiovascular disease, diabetes, kidney disease, fatty liver disease, and sleep apnea. While each factor is problematic, the main driver is abdominal obesity, from visceral fat surrounding internal organs. The best way to reduce visceral fat is aerobic exercise, strength training, and a plant-based diet.

High blood pressure means that blood pushes against artery walls more forcefully than normal. Women's blood pressure is typically lower than men's until around age 60. An estimated 41% of women develop high blood pressure after menopause. High blood pressure increases people's risks of heart attack, stroke, kidney disease, and other problems. Factors that increase women's risk of high blood pressure at midlife include menopause, elevated sympathetic nerve activity, weight gain and redistribution, stress, and genetics.

Cushing's is marked by elevated blood levels of the hormone cortisol. Far more common in women, the condition is categorized as a disease or syndrome based on what factors trigger it, which can include using corticosteroids or having a tumor on the brain's pituitary gland or elsewhere. Symptoms include a swollen face, excess belly weight, fatigue, a fatty hump between the shoulders, stretch marks, easy bruising, and slow wound healing. Cushing's can also lead to health problems such as cardiovascular disease, bone loss, and diabetes.

When blood pressure remains high despite treatment, making certain lifestyle changes can help. Examples include reducing dietary sodium and increasing dietary potassium, losing weight, limiting alcohol intake to no more than one drink per day, exercising (doing aerobics and strength training), using tools that improve medication adherence (such as an automatic pill dispenser, a medication diary, a smartphone alarm, or a reminder app), quitting smoking, getting more sleep, managing stress, and reducing caffeine intake.

Telehealth visits combined with home monitoring may be an effective way to help people reach and maintain their blood pressure goals, according to a 2025 study.

Blood pressure problems might contribute to glaucoma, a condition that damages the optic nerves and causes vision loss. If blood pressure is too low, for example, blood flow to the optic nerves might decrease. That could deprive the optic nerves of oxygen and nutrients, resulting in nerve damage. High blood pressure might also reduce blood flow to the optic nerves, by damaging the blood vessels that supply the nerves. If glaucoma gets worse despite treatment, blood pressure should be considered as a factor.

Substituting potassium-containing salt substitutes for regular salt can help lower blood pressure as well as the risk of stroke. But people should also check the sodium content in foods and eat more potassium-rich produce.