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Midlife heart health shows a link with future risk of dementia

Factors that harm your heart may be bad for your brain.


 Image: © Nik01ay/Thinkstock

During middle age, factors that leave you prone to a heart attack or stroke — high blood pressure, diabetes, and smoking — may raise your risk of developing dementia a quarter-century later, new research suggests. All three things affect your vascular (blood vessel) health.

The recent study, which adds to the growing evidence linking heart health to brain health, has elements that make findings especially reliable, says Dr. Gad Marshall, a Harvard Medical School assistant professor of neurology. "For understanding the vascular risks for dementia, this study is as close to definitive as we can get," he says.

Plant-based diets that protect your heart

Limiting animal-derived foods is only part of the story.


 Image: © AnnaPustynnikova/Thinkstock

If you're not totally sure what constitutes a plant-based diet, you're not alone. Many people believe a plant-based diet means a vegetarian diet — a family of eating patterns that omits some or all foods that come from animals (see "Vegetarian variations").

But plant-based diets don't necessarily exclude animal-derived foods. While the main focus is on plants — grains, vegetables, fruits, legumes (dried beans and peanuts), and nuts — these diets may include limited amounts of fish, meat, poultry, and dairy products.

“Fat but fit” still face higher heart disease risk

Research we're watching

People who carry excess weight but have normal blood pressure, blood sugar, and cholesterol values are sometimes dubbed "fat but fit." But they're still more likely to develop heart disease than people who aren't overweight, a new study suggests.

Researchers analyzed more than 7,600 cases of heart disease that occurred over a 12-year period in 10 European countries. They also used data from 10,000 healthy people without heart disease as a comparison group. Compared with people at a healthy weight, those who were overweight or obese had up to a 28% higher risk of developing heart disease.

Artificial sweeteners: No help, possible harm?

Research we're watching


 Image: © Highwaystarz-Photography/Thinkstock

Close to a third of Americans say they use artificial sweeteners on a daily basis. Popular examples include aspartame (Equal, Nutra­Sweet), sucralose (Splenda), and stevia (Truvia, Pure Via). They're all available in packets and are also added to soda, yogurt, and other foods.

But do these sugar substitutes actually help you lose weight? New research suggests they do not. In fact, these zero-calorie additives may have the opposite effect — and possibly even increase the risk of high blood pressure, diabetes, and heart disease.

Marijuana linked to high blood pressure risk

Research we're watching

People who smoke marijuana may face a higher risk of dying of complications of high blood pressure than people who never use the drug, new research suggests.

The study included 1,213 people ages 20 and older who were part of a larger national health survey that began in 2005. Those who said they'd ever used marijuana (57%) were considered users. Researchers then looked at data on different causes of death in 2011 and estimated the association between marijuana use with death from high blood pressure, heart disease, and stroke.

Overcoming resistant hypertension

As men live longer, more face the challenge of difficult-to-control high blood pressure.


 Image: © KatarzynaBialasiewicz/Thinkstock

High blood pressure, or hypertension, remains a common health issue for a majority of older men.

In fact, approximately 54% to 67% of men ages 65 and older suffer from the condition, which occurs when your systolic pressure (the top number on a blood pressure reading) is 140 mm Hg or higher, and your diastolic pressure (the bottom number) is 90 mm Hg or higher, according to the American Heart Association.

Is my blood pressure too low?

Ask the doctors

Q. The July 2017 issue of Harvard Women's Health Watch spoke about the potential problems related to low blood pressure when taking blood pressure medication. My readings meet the definition of low blood pressure outlined in the article, but I don't take any medication. Should I be concerned, and if so, what should I do to raise my blood pressure?

A. In general, blood pressure is deemed too low only if it causes symptoms. A normal blood pressure is defined as a reading below 120/80 millimeters of mercury (mm Hg), and some experts consider your blood pressure low only if it dips below 90/60 mm Hg. However, a low reading can be normal for some people. Your doctor probably won't be too concerned about it unless it occurs suddenly; you have an underlying health condition that could cause low blood pressure, such as heart failure; or you are experiencing symptoms such as dizziness, lightheadedness, fainting, fatigue, or nausea. Some medications, such as diuretics (water pills), some antidepressants, and beta blockers, among others, can also cause low blood pressure. But since you aren't taking any medication, this is not an issue. If you are having symptoms related to your low blood pressure, this is something you definitely want to mention to your doctor. But if you've always had low blood pressure and you're not experiencing any problems, it's likely that this is normal for your body.

A new concern about blood pressure and your brain health

Research we're watching

Last month, Harvard Women's Health Watch talked about how high blood pressure can cause a series of tiny strokes that damage your brain, increasing your risk of dementia and cognitive changes. A study in the August 8 issue of Circulation shows that this might not be the only concern when it comes to blood pressure and your mind. Researchers in Japan found that large and frequent fluctuations in blood pressure — not just high blood pressure — was associated with an increased risk of both Alzheimer's disease and vascular dementia.

The study authors asked 1,674 dementia-free participants ages 60 and older to measure their blood pressure at home, three times every morning, for about four weeks. They followed up about five years later to see who went on to develop dementia.

Shingles may raise heart attack risk

Research we're watching


 Image: © designer491/Thinkstock

People who develop the painful, blistering rash known as shingles may be more susceptible to a heart attack, according to a study in the July 11, 2017, Journal of the American College of Cardiology. Also known as herpes zoster, shingles results from a reactivation of the virus that causes chickenpox, which most adults had during childhood.

Researchers relied on a Korean health database to identify people newly diagnosed with shingles, stroke, or heart attack over 10 years. Among the nearly 520,000 people they followed for that period, just over 23,000 were diagnosed with shingles, whom they compared with a similar number of people without shingles. People who'd had shingles had a 59% higher risk of later having a heart attack and a 35% higher risk of having a stroke compared with people who did not have shingles. The risk was highest during the first year after the onset of shingles and then diminished over time.

Don’t fear pacemakers

Today's versions can correct many types of heart conditions that can keep you active and help you live longer.


 Image: © cacaroot/Thinkstock

Think of a pacemaker, and perhaps the image of a frail person stuck on the couch comes to mind. If so, you need to update your mindset. For many men, these tiny electronic devices can change their lives for the better.

"The likelihood of needing a pacemaker increases with age," says Dr. Peter Zimetbaum, a cardiologist with Harvard-affiliated Beth Israel Deaconess Medical Center. "The good news is that today's pacemakers have evolved from fixing irregular heartbeats to helping the heart mimic normal function, all of which can help many men with certain heart conditions stay more active longer."

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