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Are fibromyalgia and irritable bowel syndrome linked?

Ask the doctor

By , Senior Faculty Editor, Harvard Health Publishing; Editorial Advisory Board Member, Harvard Health Publishing
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A mature woman sitting on a couch at home holds both hands to the back of her neck, as though she is in pain.

Q. Is there a connection between IBS and fibromyalgia?

A. While there is no definite, direct connection between them, irritable bowel syndrome (IBS) and fibromyalgia do occur together in many people.

Doctors diagnose IBS based on a set of symptoms, such as abdominal pain, bloating, constipation, and diarrhea. No blood test or scan can confirm IBS, although testing may be useful to rule out other causes of gastrointestinal symptoms.

Fibromyalgia is a painful condition of the bones, muscles, and joints associated with poor quality sleep, fatigue, and multiple areas of soreness. It is also diagnosed by its symptoms. Standard tests of the joints, muscles, and bones are normal.

Several studies have noted a higher incidence of fibromyalgia among people with IBS than in those without IBS; similarly, IBS is more common among people with fibromyalgia. The meaning of this is unclear. They could have a similar (or even identical) cause, though, so far, no cause has been identified for either.

The treatment of fibromyalgia could make the symptoms of IBS worse. For example, amitriptyline (Elavil), a drug often prescribed for fibromyalgia, may make the constipation of IBS worse. And Lotronex (alosetron), prescribed for IBS, may occasionally cause muscle aches and fatigue, symptoms that are prominent with fibromyalgia.

It's possible that IBS and fibromyalgia are more closely related than is currently recognized. In the future, a better understanding of either condition could lead to new preventive measures and treatments for both.

Image: © Jana Murr/Getty Images

About the Author

photo of Robert H. Shmerling, MD

Robert H. Shmerling, MD, Senior Faculty Editor, Harvard Health Publishing; Editorial Advisory Board Member, Harvard Health Publishing

Dr. Robert H. Shmerling is the former clinical chief of the division of rheumatology at Beth Israel Deaconess Medical Center (BIDMC), and is a current member of the corresponding faculty in medicine at Harvard Medical School. … See Full Bio
View all posts by Robert H. Shmerling, MD
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