Heart Health

Stroke prevention in atrial fibrillation: Beyond anti-clotting drugs

By , Executive Editor, Harvard Heart Letter

Procedures that block or remove the source of dangerous blood clots in the heart may be an option for growing numbers of people.

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More than five million Americans have atrial fibrillation, a heart rhythm disorder commonly known as afib. During a bout of afib, the heart’s upper chambers (atria) suddenly start to quiver ineffectually. When that happens, blood tends to pool — and possibly form clots — in a small pouch that protrudes from the top of the left atrium. This ear-shaped sac is called the left atrial appendage (LAA).

About 90% of blood clots in the heart form in the LAA. These clots can escape the heart and travel to the brain, blocking blood flow and causing an ischemic stroke. Most people with afib take anti-clotting medications that help prevent these strokes. However, some people develop serious bleeding problems while taking those medications. Also known as blood thinners, these drugs are especially risky for older people who are vulnerable to head injuries from falls, increasing the risk of bleeding in and around the brain.

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About the Author

photo of Julie Corliss

Julie Corliss, Executive Editor, Harvard Heart Letter

Julie Corliss is the executive editor of the Harvard Heart Letter. Before working at Harvard, she was a medical writer and editor at HealthNews, a consumer newsletter affiliated with The New England Journal of Medicine. She … See Full Bio
View all posts by Julie Corliss

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Managing Atrial Fibrillation

Managing Atrial Fibrillation will explain what atrial fibrillation is, how to know if you have it, its causes, and the treatments available. Afib can be a complex health condition, so the more you know about it, the better you will be able to work with your doctor. If afib is monitored and treated correctly, you can minimize its symptoms and help to prevent serious complications like stroke and heart damage.

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