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Psoriasis and cancer: What’s the link?
- By Dominic Wu, MD, Contributing Editor
As a service to our readers, Harvard Health Publishing provides access to our library of archived content. Please note the date of last review or update on all articles. No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician.
The advice on ways to reduce your risk of cancer is so vague as to be, well, not much use.
Quit smoking. Most of us with the illness don’t smoke, either never did or quit long ago.
Reduce drinking. Likewise, mostly we drink little or not at all anyway.
Moderate exercise. If I already do a little more than ‘moderate’ exercise does that mean I need to reduce to moderate, or what?
Well balanced diet. I don’t think many doctors, nor patients, nor journalists know what that is. There are a dozen different theories on what is a ‘good’ diet. If the writer had some proven specifics that would be good. Otherwise, why be so vague when it means precisely nothing.
How come the researchers didnt differentiate between those psoriasis patients using drugs that could cause cancer, and those that didnt. Or did they differentiate, but it didnt make it into this report?
Thank you for your comment. The purpose of this report was to shine light on this recent article from JAMA Dermatology describing the link between psoriasis and cancer. Unfortunately, this report could not go into much detail about potential ways to reduce your risk of cancer. Furthermore, as this described link between psoriasis and cancer still needs further research, there are no clear answers about specific ways to reduce this risk of developing cancer.
The advice above mainly are previously-described modifiable risk factors when it comes to a person’s overall health. As you already know, smoking increases the risk of developing cancer significantly, and although you are not a smoker, not all patients with psoriasis are the same. These links between psoriasis and metabolic syndrome, smoking, and ETOH use are associations described in the current scientific literature, and does not always apply to every individual.
Although I am unable to describe these lifestyle modifications in detail as that is beyond the scope of this report, I would invite you to visit other reports on Harvard Health that specifically speak about these healthy habits in detail. For exercise: https://www.health.harvard.edu/topics/exercise-and-fitness. For specific recommendations on healthy eating, please visit: https://www.health.harvard.edu/staying-healthy/whats-new-in-nutritional-guidelines. I hope these links can provide much more detail for what you are looking for.
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Inflammatory Skin Conditions: Eczema, seborrheic dermatitis, and psoriasis
The flaking and itchy skin caused by eczema, seborrheic dermatitis, and psoriasis can be very uncomfortable and often leads to feeling self-conscious or alone during flare-ups. Fortunately, there is much you can do to tame these inflammatory skin conditions. It may take some trial and error, but chances are that you will find a strategy that works for you. This guide will help you understand your options. You’ll learn about what causes these skin conditions; typical symptoms of each; how these conditions are diagnosed and treated; and what you can do on your own (and with your doctor) to manage them.
Types of psoriasis
Several forms of psoriasis exist. While distinct, they may overlap in particular individuals.
This is the most common type of psoriasis. Although it can develop at any age, it most commonly appears from young adulthood to middle age. Symptoms include raised patches of red, inflamed skin, covered with silvery-white flaky scales. Plaques may crack, ooze, and bleed. They can develop anywhere, but are most common on elbows and knees. They also commonly develop on the scalp. Affected areas may itch or hurt.
This type of psoriasis usually develops suddenly in childhood or adolescence. It may be triggered by an infection, usually strep throat. Guttate psoriasis is characterized by small red, scaly bumps that are scattered across the arms and torso (including the back, chest, and abdomen).
Inverse (intertriginous) psoriasis
This form of psoriasis typically appears in folds of skin, such as under the arm, behind the knee, under the breasts, or in the groin area. Symptoms include bright red areas on the skin that may be shiny and smooth. Inverse psoriasis can occur at the same time as other forms of psoriasis. It is sometimes mistaken for a fungal or yeast infection of the skin.
In this type of psoriasis, pus-filled blisters (pustules) develop on red, inflamed skin. This type of psoriasis most often affects the hands and feet. It is most common in adults. Symptoms include pustules on the palms or fingers, or on the soles of the feet or toes. These pustules may crack and cause painful fissures in the skin.
A rare but life-threatening subtype of pustular psoriasis, von Zumbusch psoriasis, requires immediate medical attention. In this condition, large areas of fiery red, painful skin spread quickly over much of your body. Pustules develop soon afterwards. Your skin may peel off in sheets, and you may develop fever and chills. This type of psoriasis requires immediate medical attention, as it can disrupt the skin’s ability to maintain internal temperature and can lead to shock. It’s also known as acute generalized pustular psoriasis.
When psoriasis affects the nails, it may cause a scattering of pits, similar to pinpricks, across the nail. It may also cause brown “oil spots” to appear on the nail or cause the nail to separate from its bed. In the most severe cases, nails may grow thick and crumble.