Diabetes Archive

Virtually everyone carries the bacteria Clostridioides difficile, or C. diff. But half a million Americans a year develop a serious C. diff infection due to a gut microbiome imbalance. It disproportionately strikes people in hospitals and nursing homes, and can recur repeatedly.

Even slightly elevated blood sugar levels—a condition known as pre-diabetes—may raise the risk of cardiovascular problems. But attention to weight loss and greater use of medications to lower blood pressure and cholesterol appear to reduce the risk.

According to a 2023 study, people who consumed 25% or more of their daily calories from added sugars had an 88% higher risk of developing kidney stones compared with those who kept their added sugar intake to less than 5% of their daily calories.

A newer class of medications used to treat type 2 diabetes called glucagon-like peptide-1 (GLP-1) receptor agonists has gained attention because of their impressive weight-loss results—in many cases, 10% to 20% of a person's body weight. Versions of two of these GLP-1 receptor agonists, liraglutide (Saxenda) and semaglutide (Wegovy), are FDA-approved for weight loss, even for people without diabetes. However, there isn't enough evidence to know whether these drugs might be beneficial or dangerous for people who are not diagnosed with diabetes or obesity.

White spots on fingernails are common and have many possible causes. These include minor trauma to the fingers, wearing nail polish for prolonged periods, fungal infections, low iron levels, kidney disease, or liver cirrhosis.

Some doctors feel it's unlikely that editing people's genes will help prevent them from getting Alzheimer's disease. It's not just because attempts to edit genes inside the cells of living animals are in their infancy. It's also because most cases of Alzheimer's disease occur in older adults, and those cases do not appear to be caused just by a few defective genes. Lifestyle—particularly exercise, diet, and the amount of high-quality sleep—affects the risk of developing Alzheimer's at least as much as genes.

People who get most of their recommended weekly physical activity over one or two days may lower their heart disease risk just as much as those who are active more regularly throughout the week. Evidence also suggests there's no particular benefit to exercising at certain times of the day, including with respect to mealtimes. So people should be physically active whenever they find it to be most convenient.