If depression meds don't work, switching sooner may be best

Published: November, 2012

When the first medication you take for depression doesn't work, should your doctor raise the dose or try a different one? A study in the Journal of Clinical Psychopharmacology found that switching relatively early does not worsen symptoms, and may lead to slightly better results over the long term.

The study involved 840 people being treated for depression. They started on escitalopram (Lexapro), a common antidepressant. In 70% of people, the escitalopram did not start to work after a month.

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