Diseases & Conditions

Why are cold symptoms worse at night?

Ask the doctor

By , Editor in Chief, Harvard Women's Health Watch; Editorial Advisory Board Member, Harvard Health Publishing; Contributor

photo of a woman in bed sleeping; next to her on the night stand are a box of tissues and a blister pack of cold medication

Q. My cold symptoms seem to be improving during the day, but at night they get worse again. Why does that happen?

A. Frustrating, isn't it? But you're not imagining that your cough and congestion ramp up just when it's time to hit the hay. The circadian rhythm — our 24-hour internal clock — signals immune cells to become more active at night. When these cells pinpoint germs, they fight them off by creating inflammation, which makes respiratory symptoms worse.

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About the Author

photo of Toni Golen, MD

Toni Golen, MD, Editor in Chief, Harvard Women's Health Watch; Editorial Advisory Board Member, Harvard Health Publishing; Contributor

Dr. Toni Golen is a physician specializing in obstetrics and gynecology, practicing in Boston. Dr. Golen completed her residency training at George Washington University Medical Center in 1995, and is an associate professor at Harvard Medical … See Full Bio
View all posts by Toni Golen, MD

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