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Harvard Health Blog
A conversation with Dr. Jerry Avorn about drugs and the drug industry
- By Patrick J. Skerrett, Former Executive Editor, Harvard Health
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Drugs are the extreme poisoning which kills human body slowly.As a result asian country they not fully rely on drugs for medicine. Thanks
Genetics are allowed to differ in their active Pharm product by a significant %. eg, if brand contains 5mg of a product, generic may contain 4.8mg ,and still allowed to label as 5mg. I stand to be corrected
I just saw Dr Avorn on PBS say that all generics are equal to the brand name and believe he is doing a disservice to us with such a broad statement. I know from personal experience that this is not true. I have been taking Toprol XL for high blood pressure for ten years and when given a generic by a new pharmacy, I soon realized that it wasn’t working as well, endangering my life. My understanding is that the binder in the generic is different and unregulated and that the full absorption of the active ingredient was inhibited by the inefficient binder. I switched back to the brand name and my blood pressure returned to healthy levels.
I salute Dr Avorn’s efforts at counter-detailing but some generics are just not equivalent. I also doubt seriously if drugs manufactured in China get the same scrutiny as those made in the US (if there still are any).
I beg to disagree with the general statement that generics are as good as brand names. I have trigeminal neuralgia and am on tegretol XR for it. Works great. My pharmacist substituted the generic carbamazapine xr and all the pain came back. My brillian neurologist said that some medication are difficult to make… this being one of them. Maybe the good doctor needs to see which generics work and which don’t. Or is that another book?!?
This guy DOES NOT know what he is talking about. I experienced first hand the difference between Welbutrin and a generic brand when my insurance refused to pay for Welbutrin. It took me a while to figure out what was wrong with me and why I was crying and depressed. I went back on Welbutrin at my expense and was fine again.
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Although drug remains to be an important aspect to our everyday living but it has its advantages and disadvantages as well. All drugs have its own side effects. Sometimes it can become a real killer of your life. And also in certain part of the world the medicine does not come as it gets branded. People at certain times get the substandard product of it. So it is better to avoid using drugs at abundance.
Genetics are allowed to differ in their active Pharm product by a significant %. eg, if brand contains 5mg of a product, generic may contain 4.8mg ,and still allowed to label as 5mg. I stand to be corrected.
drug is a slow killer.that’s why in some asian country they not fully rely on drugs for medicine
Statins have prevented enormous amounts of sickness and death from heart disease; they are fantastic drugs. But it’s also probably fair to say that we are not as good as we should be about studying side effects that don’t land people in the hospital—or kill them. I think we have a good handle on statins and rhabdomyolysis, the muscle breakdown that can be fatal.
this is gokul from india.
the drugs plays a vital role in human life.
ya me too have a question on generic drugs
how are the differ from non generic ?
could you pls explain ?
Well said Sir. But in our part of the world (West Africa) generics MAY not be as good as the branded. We get substandard products from India and other places.
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