Harvard Heart Letter

Getting to the heart of kidney disease

Heart disease and kidney failure are linked by two powerful underlying risk factors: diabetes and high blood pressure, each of which damages the heart and kidneys independently. Underlying the connection is a breakdown in metabolic signaling that affects blood sugar, blood pressure, sodium levels, and fat storage. Both environmental and genetic forces are probably involved in creating the malfunction. Keeping blood pressure and blood sugar levels in an acceptable range can help preserve heart health and kidney function.
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