Lower doses of a combination of drugs may be effective.
Approximately one in three Americans has high blood pressure, but only about half of those who do have the condition under control. One common reason: they stop taking their medications, often because of troublesome side effects such as weakness, fatigue, or a dry cough. However, taking smaller doses of several different blood pressure drugs may be a good way to address these issues, a new analysis suggests.
Researchers pooled findings from 42 studies involving more than 20,000 people with high blood pressure. All had been randomly assigned to take a placebo or one or more blood pressure drugs in varying combinations and dosages. (For the American Heart Association's list of common blood pressure drugs, including their possible side effects.
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