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Medication side effects Archive

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Follow medication instructions

It appears that adverse drug events that lead to visits to the emergency department are increasing among older adults.

New prescription? Talk to your pharmacist

A conversation with this health professional can help you avoid making harmful mistakes.


 Image: wavebreakmedia/Thinkstock

When your pharmacist hands you your pills, he or she is likely to ask, "Any questions?" This is an invitation to tap into a vast store of knowledge—and one you should accept. A few minutes with your pharmacist may spare you some serious health consequences.

"People are often in the dark regarding the purpose of their medication," says Dr. Gordon Schiff, associate professor of medicine at Harvard Medical School. Although prescriptions come with a lengthy package insert containing detailed information about the drug, the information is often written in technical terms and printed in microscopic type. The lack of clear information and the confusion and misunderstandings that result figure into more than a million preventable medical complications annually.

How does the new vaginal product alleviate pain during intercourse?

Intrarosa, a vaginal insert containing dehydroepiandosterone (DHEA), improves vaginal lubrication to alleviate pain during intercourse.

Diuretic blood pressure drug linked to fewer hip fractures

In a large, long-term clinical trial, people taking the diuretic chlorthalidone had significantly fewer hip fractures than those taking the calcium-channel blocker amlodipine or the ACE inhibitor lisinopril.

Are some painkillers safer for your heart than others?

Despite new research, the answer is unclear. Use caution when taking any pain medication on a routine basis.


Image: iStock

People with aching joints from arthritis—which affects nearly one in four adults—often rely on drugs known as NSAIDs to ease the pain of this often-debilitating condition. These popular medications also relieve headaches, cool fevers, and dampen inflammation. But with the exception of aspirin, most NSAIDs pose a risk to the cardiovascular system, notes Harvard professor Dr. Elliott Antman, a cardiologist at Brigham and Women's Hospital.

"Taking NSAIDs routinely over a long time period can raise the risk of blood clots, increase blood pressure, and accelerate cardiovascular disease," says Dr. Antman. While the danger is greatest in people with heart disease, it's also present in people without any signs of the disease.

Is my medication causing these side effects, or is it just aging?

Tracking your progress and symptoms can help you discern the difference.


Image: YakobchukOlena/Thinkstock

You probably know that when you take a medication, you need to tell your doctor about any side effects that develop. But being aware of side effects can be challenging when you're older. "In many cases, the signs of aging are similar to side effects of medications," says Joanne Doyle Petrongolo, a pharmacist at Harvard-affiliated Massachusetts General Hospital.

Similarities

What you should do

To determine if your symptoms are drug side effects or signs of aging, Doyle Petrongolo recommends keeping good records of your health issues and medication changes. "Keep a chart or a log of all medications taken, and record the medication start date. If a side effect is noted within a few days or weeks of starting a medication, then it is more likely that the symptom is medication-related," she explains.

It may be weeks or months before a symptom develops, but don't wait too long to report a symptom, especially if it interferes with your daily activity. "If it lingers for several weeks, then it is a good idea to speak with a doctor or pharmacist to determine the cause," says Doyle Petrongolo.

The fix

Does it matter how you lower your cholesterol?

Certain cholesterol-lowering medications—namely, ezetimibe (Zetia) and drugs known as bile acid binders—also appear to be effective at lowering cholesterol and reducing the risk of serious cardiovascular events. 

When is it okay to split medication in half?

Splitting a pill into two equal halves is sometimes necessary when needing to adjust dosage, or as a means to save money buy purchasing higher-dose pills. However, splitting is not safe for all pills, so a person should always consult a pharmacist or doctor.

Drugs to prevent heart attacks may also lessen their severity

Medications such as aspirin, statins, ACE inhibitors, and beta blockers are prescribed to certain patients to lower the chance of a first or repeat heart attack. New research shows that they also may reduce the severity of attacks that do occur.

Is your antidepressant making life a little too blah?

Some drugs go too far, dulling emotions across the spectrum. A dose adjustment or a switch to a different medication can help.


 Image: Wavebreakmedia/Thinkstock

When your doctor prescribes a medication for depression, the goal is to reduce painful feelings of sadness or hopelessness. The majority of people taking the most commonly prescribed antidepressants—selective serotonin reuptake inhibitors (SSRIs)—improve substantially. But sometimes, SSRIs go beyond improving mood and make a person feel too little emotion. "Some people feel like they've lost the richness of daily life," says Dr. Michael Craig Miller, assistant professor of psychiatry at Harvard Medical School.

Serotonin and SSRIs

Too effective?

Scaling back the intensity of moods is often the goal. "It's a huge relief if you're very irritable, easily upset, or feeling overly burdened by stress," says Dr. Miller.

But for some people, the reduction in intensity can be experienced as a "blunting" or "dulling" of their emotions. "You might not cry at a movie's happy ending or laugh with the same gusto. Or you might feel apathetic and not get the same kick out of doing things you enjoy, like playing golf or painting," Dr. Miller explains.

Sometimes the blunting affects sexual response. "Some people will say they're not having the same sexual pleasure," says Dr. Miller.

What you should do

 

 

 

 

 

 

 

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