Endorphins: The brain's natural pain reliever

Endorphins can also release stress and create a feeling of well-being.

By , Former Executive Editor, Harvard Women's Health Watch

photo of a woman lying on her back while meditating, in a relaxed position with her eyes closed

Endorphins are the body's natural painkillers. Released by the hypothalamus and pituitary gland in response to pain or stress, this group of peptide hormones both relieves pain and creates a general feeling of well-being.

The name of these hormones comes from the term "endogenous morphine." "Endogenous" because they're produced in our bodies; morphine refers to the opioid painkiller whose actions they mimic.

About 20 different types of endorphins exist. The best studied of these is beta-endorphin, which is the one associated with the runner's high. We also release endorphins when we laugh, fall in love, have sex, and even eat a delicious meal.

How to release endorphins

You can increase your body's endorphin release by engaging in these activities:

  • Exercise. A moderately intense pace, whether you're walking fast or doing another form of aerobic activity, seems to be best for releasing endorphins.
  • Acupuncture. An effective way to release endorphin is with pressure points. Placing fine needles into the skin at specific points around the body triggers the release of endorphins.
  • Meditation. Breathing deeply and focusing your brain calms your mind and eases pain.
  • Sex. These hormones are the reason for that blissful feeling many of us get after having sex. Experts believe that endorphins promote the release of other hormones that are involved in feelings of love.
  • Playing music. When you sing, dance, or bang on a drum, you do more than entertain others. You also release a rush of endorphins, which research suggests might increase tolerance to pain.
  • Laughter. A good belly laugh can do wonders for your state of mind. Along with releasing endorphins, laughter alters levels of serotonin and dopamine.
  • Ultraviolet light. It's no wonder that some people feel happy when they spend time outdoors in the sun. Ultraviolet light stimulates the release of beta-endorphins in the skin.

Endorphins are just one of the four feel-good hormones. To learn more about the others and how they work, head to the beginning of this series.

Image: microgen/Getty Images

About the Author

photo of Stephanie Watson

Stephanie Watson, Former Executive Editor, Harvard Women's Health Watch

Stephanie Watson was the Executive Editor of the Harvard Women’s Health Watch from June 2012 to August 2014. Prior to that, she worked as a writer and editor for several leading consumer health publications, including WebMD, … See Full Bio
View all posts by Stephanie Watson

About the Reviewer

photo of Howard E. LeWine, MD

Howard E. LeWine, MD, Chief Medical Editor, Harvard Health Publishing

Dr. Howard LeWine is a practicing internist at Brigham and Women’s Hospital in Boston, Chief Medical Editor at Harvard Health Publishing, and editor in chief of Harvard Men’s Health Watch. See Full Bio
View all posts by Howard E. LeWine, MD

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