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Is Viagra safe to take with Eliquis?

Ask the doctor

By , Chief Medical Editor, Harvard Health Publishing; Editorial Advisory Board Member, Harvard Health Publishing
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Two pill bottles on their sides with pills spilled out; the round yellow pills and beige square pills are mixed together in front of the bottles.

Q. I take Eliquis because I have atrial fibrillation. Would taking Viagra be dangerous?

A. Apixaban (Eliquis) is one of the commonly prescribed anticoagulant drugs in people with atrial fibrillation to help prevent a stroke. Some people take rivaroxaban (Xarelto) or warfarin (Coumadin) for a similar indication.

Sildenafil (Viagra) may very slightly increase the risk of bleeding, such as bloody nose, in people taking an anticoagulant. This is also true for the other commonly used drugs to treat erectile dysfunction (ED), such as tadalafil (Cialis) and vardenafil (Levitra).

However, you may want to be cautious if you tend to develop a fast heart rate with your atrial fibrillation when engaging in physical activity. Some people with atrial fibrillation develop low blood pressure when they have an increased heart rate. Viagra and the other ED drugs mentioned above could exaggerate the drop in blood pressure during sex.

When starting Viagra or a similar drug, it's safest to start with a low dose as directed by your doctor.

Also, ask your doctor or pharmacist if any of your other drugs could interact with the Viagra.

Image: © Jeffrey Coolidge/Getty Images

About the Author

photo of Howard E. LeWine, MD

Howard E. LeWine, MD, Chief Medical Editor, Harvard Health Publishing; Editorial Advisory Board Member, Harvard Health Publishing

Dr. Howard LeWine is a practicing internist at Brigham and Women’s Hospital in Boston, Chief Medical Editor at Harvard Health Publishing, and editor in chief of Harvard Men’s Health Watch. See Full Bio
View all posts by Howard E. LeWine, MD
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