Medications to aid weight loss may be helpful for people with obesity, a condition that puts a heavy burden on the heart. Some early weight-loss medications proved risky for the heart, but the approval of four new drugs in the past two years has expanded the options for treating obesity. However, the benefits are modest at best, helping people lose an average of about 5% of their body weight over six to 12 months. People may need to try several different medications before finding one that works for them.
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