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Respiratory health

What is pleurisy?

Ask the doctor

By , Chief Medical Editor, Harvard Health Publishing; Editorial Advisory Board Member, Harvard Health Publishing
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Three-dimensional illustration of a human body in blue on a black background, with the lungs highlighted in glowing orange.

Q. What is inflammation of the rib cage lining called? Is it a serious condition?

A.The lining inside the rib cage and around the lung is called the pleura. Inflammation of this lining is known as pleuritis, but the more commonly used term is pleurisy.

Normally there is a very tiny amount of fluid between the pleural surface that surrounds the lung and the pleural surface that covers the inside of the rib cage. The fluid is the grease that allows the two smooth surfaces to glide over each other as you breathe in to expand the lungs and breathe out as the lungs contract.

Many years ago when tuberculosis (TB) was more common in the United States, pleurisy was often associated with TB. So, a diagnosis of pleurisy could be scary.

While pleuritis is quite common in the U.S. today, it is very rarely caused by TB.

The main symptom of pleuritis is pain when you take a deep breath. Most often the cause of pleuritis cannot be determined, and the symptoms usually go away after a few days. A viral infection inflaming the pleura is a likely possibility.

There are many other causes of pleuritis. It can be a symptom of something more serious, such as a pulmonary embolus (a blood clot that travels to the lung) or pneumonia. Almost always there will be other symptoms, not just chest pain with a deep breath.

Any of these additional symptoms require immediate medical evaluation or at least an immediate call for medical advice:

  • shortness of breath
  • fever
  • lightheadedness
  • loss of consciousness (passing out).

Image: © libre de droit/Getty Images

About the Author

photo of Howard E. LeWine, MD

Howard E. LeWine, MD, Chief Medical Editor, Harvard Health Publishing; Editorial Advisory Board Member, Harvard Health Publishing

Dr. Howard LeWine is a practicing internist at Brigham and Women’s Hospital in Boston, Chief Medical Editor at Harvard Health Publishing, and editor in chief of Harvard Men’s Health Watch. See Full Bio
View all posts by Howard E. LeWine, MD
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