By the way, doctor: Does long-term use of Prilosec cause stomach cancer?

Q. I've been taking Prilosec for over a year for GERD. Recently, I read that long-term use of proton pump inhibitors increases the risk of certain gastric cancers. Your opinion?

A. Proton pump inhibitors (PPIs) have revolutionized the treatment of gastroesophageal reflux disease (GERD), in which stomach acid flows back into the esophagus and causes heartburn. Brand-name drugs in this class include Prilosec, Nexium, Prevacid, Protonix, Pantoloc, and Aciphex. They all shut down the proton pump, an enzyme involved in the production of stomach acid.

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