Recent Blog Articles

Cancer

New blood test for colon cancer screening: Questions remain

colon-cancer-screening
July 18, 2016

Disclaimer:

As a service to our readers, Harvard Health Publishing provides access to our library of archived content. Please note the date of last review or update on all articles. No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician.

Comments

Roger P
August 4, 2016

EpiPro Colon and the Cologuard test are not evidenced based medicine – the Second Generation FIT test and Colonoscopy are. EpiPro Colon approaches or exceed a Colonoscopy in terms of cost, and Cologuard may or may not be covered by insurance providers. Colonoscopy is always covered, and Second Generation FIT (Pinnacle BioLabs) is $25 and OTC cleared. Most thought leaders think the Cologuard test is frivolous (in terms of government dollars) and EpiPro Colon is downright obnoxious – combine that with it not being as sensitive and specific as a FIT test? It’s a rather silly “argument”.

-Roger

Roger P
July 30, 2016

While the author did not name Epi Pro Colon by name, she refers to it, even in the title of the article. And her information is accurate. Colonoscopy is the gold standard, and should be performed every 10 years. FIT is second to none. It has been widely available and widely studied and has been proven to find cancer and find it early.
FIT in the hands of a doctor will screen 1000 times the patients Epi Pro Colon or Cologuard will. And FIT is also available without an Rx or without a doctor visit. You can learn more and buy one (for just $25)
-Roger

David Bull
July 19, 2016

There are two additions to this article. First – The blood test, Epi proColon, is a methylated Septin 9 DNA blood which was, in fact, studied and found to have non-inferior sensitivity to FIT (Johnson PLOS ONE 2014). The intended patient population for Epi proColon are those who are unwilling and unable to perform the typical CRC Screening Test – as mentioned in the article.

Second – the USPSTF Recommendation Statement (June 2016) was recently released which includes 3 additional recommended Screening Tests (not mentioned in the article) – FIT DNA, CT Colonography, as well as, SEPT9 DNA.

Jay Stephens
July 19, 2016

What is the test’s name? What is it measuring?

David Bull
July 19, 2016

The name of the test is Epi proColon. It measures methylated Septin 9 DNA.

Robert Miller
July 18, 2016

INSANE!!! No mention of Cologuard which rivals a colonoscopy and is far better than a fecal blood test. In fact a Cologuard test INCLUDES a fecal blood test and FEATURES a DNA test that finds pre- cancerous conditions. A blood test does have “limitations” like it only can find Colon cancer after it is in your blood or Stage I long after you may have cancerous polyps that could be removed.

Cologuard can find Colon cancers that a colonoscopy misses.

Commenting has been closed for this post.

Harvard Health Publishing Logo

Thanks for visiting. Don't miss your FREE gift.

The Best Diets for Cognitive Fitness, is yours absolutely FREE when you sign up to receive Health Alerts from Harvard Medical School

Sign up to get tips for living a healthy lifestyle, with ways to fight inflammation and improve cognitive health, plus the latest advances in preventative medicine, diet and exercise, pain relief, blood pressure and cholesterol management, and more.

Harvard Health Publishing Logo

Health Alerts from Harvard Medical School

Get helpful tips and guidance for everything from fighting inflammation to finding the best diets for weight loss...from exercises to build a stronger core to advice on treating cataracts. PLUS, the latest news on medical advances and breakthroughs from Harvard Medical School experts.

BONUS! Sign up now and
get a FREE copy of the
Best Diets for Cognitive Fitness

Harvard Health Publishing Logo

Stay on top of latest health news from Harvard Medical School.

Plus, get a FREE copy of the Best Diets for Cognitive Fitness.