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Probiotics — even inactive ones — may relieve IBS symptoms

June 22, 2020

About the Author

photo of Anthony Lembo, MD

Anthony Lembo, MD, Contributor

Anthony Lembo, MD, is Director of the GI Motility and Functional Bowel Disorders Program at Beth Israel Deaconess Medical Center and Professor of Medicine at Harvard Medical School in Boston, MA. Dr. Lembo earned his medical … See Full Bio
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Nelly Genova
July 2, 2020

Why are you ignoring tyhe role of Helicobacter pilory ?

Martha Paradeis
June 30, 2020

This is an interesting study. Recent information about taking probiotics has been contradictory or inconclusive; many professionals end up not recommending probiotics routinely, unless one is trying to replace normal gut flora after a course of antibiotics.
I would also like to know where to obtain inactive bifidobacterium bifidum MIMBb75.

M. Mansoori
June 30, 2020

Dear Dr. Lembo,
IBS is not chronic gut-brain disorder, and probiotics will not cure or make symptoms better.
Matter of fact, is lack of some digestive enzymes which the one with ibs his/hers intestine stop producing the said enzymes.
Those with IBS should take digestive enzyme before the meal,
have gluten free products, they should be 100% okay.
I have so far 2 cases proven.
Finally, please note that digestive enzymes are not the same as probiotics.

Elizabeth J Nelson
June 29, 2020

I was diagnosed with IBS, a 75 year old female over one year ago. I believe my problems started after suffering several bouts of UTI and overly prescribed antibiotics. I believe this treatment threw off my flora balance. My gastroenterologist prescribed low dose budesonide which I do not want to depend for the rest of life which he said many of his patients are doing.

Bernita Capstick
June 29, 2020

How many billion would be considered an effective daily dosage?

Virginia Rinaudo
June 29, 2020

Is this strain of inactive probiotic available to the general public?

carmen kobashigawa
June 29, 2020

Hi, I have a question. Is there a significant difference between the results obtained from the study with live and inactivated probiotics?
Are there studies with MIMBb75 in vivo?
Sorry for the spelling mistakes, English is not my native language.

June 23, 2020

Another positive result of taking probiotics for me has been a reduction of inflammation throughout the body. Before beginning them I would have swelling and stiffness in my feet and ankles, especially in the evenings after sitting for awhile. Since consistently taking the probiotics, this swelling is gone and I no longer have the pain and stiffness that resulted. They have been a life changer for this middle ager.

Everly Lewis
June 23, 2020

I find this article interesting and would like to add that I have experienced relief from IBSc symptoms after having been on probiotics containing Lactobacilli. My symptoms are not totally gone and hence my decision to try a probiotic containing Bifidobacteria.

James Taylor
June 22, 2020

How do I get the inactive bacteria for my IBS.

Commenting has been closed for this post.

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Managing Irritable Bowel Syndrome

IBS is a gastrointestinal disorder in which your gut becomes more sensitive and the muscles of your digestive system have abnormal contractions that affect your bowel movements. IBS cannot be cured, but the good news is it can be managed to minimize the effect on your overall health and quality of life. This report explores how your digestive system works and what science knows about this mysterious disorder. We’ll cover the types of IBS, how it’s diagnosed, and best of all, what you can do to control IBS instead of having it control you.

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