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Meningitis vaccines: What parents need to know

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Published: August 08, 2018
  • Author: Claire McCarthy, MD,

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Comments

vinu arumugham
August 26, 2018

Before the introduction of the Menactra and Menveo vaccines in 2005 and 2010 respectively, incidence rate of meningococcal disease in the US was ~1 in 100,000.

https://www.cdc.gov/meningococcal/surveillance/index.html
https://www.historyofvaccines.org/content/articles/meningococcal-disease

The Menveo package insert https://www.fda.gov/downloads/biologicsbloodvaccines/vaccines/approvedproducts/ucm201349.pdf

says:
“Among subjects with symptom onset within 42 days of vaccination (days 12, 25, 29), 3/12049 [0.02%, 95% CI: (0.01% ,0.07%)] MENVEO recipients and 0/2877 [0%, 95% CI: (0%, 0.13%)] control recipients were diagnosed with Kawasaki Disease.”

This article explains why Kawasaki disease occurs following Menveo.

SIDS, Kawasaki Disease and narcolepsy: Same mechanism, different vaccines.
https://www.bmj.com/content/360/bmj.k1378/rr-11

So we are trading a 1 in 100,000 meningococcal disease rate for a 1 in 4000 Kawasaki disease rate?

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