Recent Blog Articles

Harvard Health Blog

A monthly shot for opioid addiction: An option for some

April 1, 2016

About the Author

photo of Wynne Armand, MD

Wynne Armand, MD, Contributor

Dr. Wynne Armand is an associate physician at Massachusetts General Hospital (MGH), where she provides primary care; an assistant professor in medicine at Harvard Medical School; and associate director for MGH Center for the Environment and … See Full Bio
View all posts by Wynne Armand, MD


As a service to our readers, Harvard Health Publishing provides access to our library of archived content. Please note the date of last review or update on all articles.

No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician.


May 10, 2016


Livescan Noc
April 2, 2016

It will help a lot of people

Jennifer Viera
April 1, 2016

This week a study was published today in The New England Journal of Medicine. It showed that in a randomized controlled clinical trial, Vivitrol significantly prevented relapse to opioid dependence in men previously substance-dependent and involved with the criminal justice system. Here’s a link to the study. Full text is free.

Wynne Armand
April 4, 2016

Thank you for your comment regarding this new study publication. The results are encouraging: long-acting naltrexone was a more effective treatment option in this patient population when given in addition to the usual community counseling programs (21% lower relapse rate during the 6-month trial). It is also encouraging that there were fewer overdoses both during and after completion of the 6-month naltrexone treatment. Unfortunately, the benefit of relapse prevention in this naltrexone study group was only present during the 6 months of treatment with injections, as the rate of opioid use was similar in both groups at the 12-month and 18-month follow-ups.

Commenting has been closed for this post.

Free Healthbeat Signup

Get the latest in health news delivered to your inbox!

Harvard Health Publishing Logo

Thanks for visiting. Don't miss your FREE gift.

The Best Diets for Cognitive Fitness, is yours absolutely FREE when you sign up to receive Health Alerts from Harvard Medical School

Sign up to get tips for living a healthy lifestyle, with ways to fight inflammation and improve cognitive health, plus the latest advances in preventative medicine, diet and exercise, pain relief, blood pressure and cholesterol management, and more.

Harvard Health Publishing Logo

Health Alerts from Harvard Medical School

Get helpful tips and guidance for everything from fighting inflammation to finding the best diets for weight loss...from exercises to build a stronger core to advice on treating cataracts. PLUS, the latest news on medical advances and breakthroughs from Harvard Medical School experts.

BONUS! Sign up now and
get a FREE copy of the
Best Diets for Cognitive Fitness

Harvard Health Publishing Logo

Stay on top of latest health news from Harvard Medical School.

Plus, get a FREE copy of the Best Diets for Cognitive Fitness.